Auditory and Vestibular Systems, Lateral LineIntracellular responses of the rat cochlear nucleus to sound and its role in temporal codingPaolini, Antonio G.1,3; Clark, Graeme M.1,2; Burkitt, Anthony N.2Author Information 1The Human Communication Research Centre, Department of Otolaryngology, University of Melbourne, Royal Victoria Eye and Ear Hospital, 32 Gisborne Street, East Melbourne 3002, Australia 2Cooperative Research Centre for Cochlear Implant, Speech and Hearing Research, Melbourne, Australia 3Corresponding Author: Antonio G. Paolini ACKNOWLEDGEMENTS: This work was funded by the Bionic Ear Institute, Human Communication Research Centre, Hearing Research Foundation and Cooperative Research Centre for Cochlear Implant. Website publication 3 October 1997 Received 3 August 1997; accepted 17 August 1997 NeuroReport: October 20th, 1997 - Volume 8 - Issue 15 - p 3415-3421 Buy Abstract THE anteroventral cochlear nucleus (AVCN), the first centre of the central auditory pathway, contains globular bushy cells, which are unique in their ability to produce fast excitatory post-synaptic potentials (EPSPs). Using in vivo intracellular recordings in the rat AVCN we examined these fast EPSPs in relation to temporal coding. At frequencies up to 2.5 kHz, EPSPs were evoked on successive sine waves of the stimulus with EPSP summation limited. This one-to-one relationship between the EPSPs and the sound wave period was present at higher frequencies and over a greater intensity range than for action potentials. These results suggest that temporal coding is possible in globular bushy neurones by their ability to extract temporal information through fast processing of convergent presynaptic input. © Lippincott-Raven Publishers.