Cognitive Neuroscience and NeuropsychologyRisk for non-insulindependent diabetes in the normoglycaemic elderly is associated with impaired cognitive functionVanhanen, Matti1,5; Koivisto, Keijo1; Karjalainen, Leena2; Helkala, Eeva-Liisa3; Laakso, Markku2; Soininen, Hilkka1; Riekkinen, Paavo Sr4Author Information 1Departments of Neurology, POB 1627, FIN-70211 Kuopio, Finland 2Internal Medicine, POB 1627, FIN-70211 Kuopio, Finland 3Community Health and General Practice, POB 1627, FIN-70211 Kuopio, Finland 4A.I. Virtanen Institute of Kuopio University and University Hospital, POB 1627, FIN-70211 Kuopio, Finland 5Corresponding Author: Matti Vanhanen ACKNOWLEDGEMENT: This study was supported by the Medical Research Council of the Academy of Finland. Received 28 January 1997; accepted 18 February 1997 NeuroReport: April 14, 1997 - Volume 8 - Issue 6 - p 1527-1530 Buy Abstract WE studied cognitive function in normoglycaemic elderly subjects at different risk levels for developing non-insulin-dependent diabetes mellitus (NIDDM) and in patients with NIDDM. Risk for NIDDM was considered increased if both 2 h glucose and insulin values on oral glucose tolerance testing were higher than the median in normoglycaemic subjects, and low if the respective values were lower than the median. The increased risk group showed impairment on tests of immediate and delayed memory, attention, visuomotor speed and verbal fluency. Moreover, the increased risk group did not differ from patients with NIDDM on any cognitive tests. Our results suggest that increased risk for NIDDM is associated with widely affected cognitive function in the normoglycaemic elderly, highlighting the importance of healthy living habits. © Lippincott-Raven Publishers.