Article: PDF OnlyArmstrong R. A.; Myers, D.NeuroReport: March 1992 - p 262-264 Buy Abstract THE density and spatial pattern of immunostained β/A4 deposits and mature senile plaques (SP) stained by the Glees method were compared in Alzheimer's diseased brain. Thirty-seven percent of the variance in Glees SP density in a tissue could be explained by β/A4. Both lesions were clustered with the β/A4 clusters often larger than the Glees SP clusters. β/A4 and Glees SP cluster size were not correlated in a tissue. The size of Glees SP clusters was positively correlated with SP density but no correlation could be detected for β/A4. Hence, the density and spatial pattern of β/A4 deposits in most tissues did not predict the development of Glees SP. © Lippincott-Raven Publishers.