Motor Systems: PDF OnlyGamma-aminobutyric acid induces feeding behaviour in the marine mollusc, Clione limacinaArshavsky, Yuri L.; Gamkrelidze, Georgi N.; Orlovsky, Grigori N.2,; Panchin, Yuri V.; Popova, Lioudmila B.1Author Information Institute of Problems of Information Transmission, Acad. Sci. of USSR, Moscow, USSR 1A.N. Belozersky Laboratory of Molecular Biology and Bioorganic Chemistry, Moscow State University, Moscow, USSR 2Nobel Institute for Neurophysiology, Karolinska Institutet, Box 60400, S10401, Stockholm, Sweden NeuroReport: April 1991 - Volume 2 - Issue 4 - p 169-172 Buy Abstract THE effects of gamma-aminobutyric acid (GABA) on the behaviour of the marine pteropod mollusc Clione limacina were studied. In intact molluscs, injection of GABA evoked the consummatory stage of feeding behaviour, i.e. protracting the tentacles, opening the mouth, catching and swallowing prey, as well as some acceleration of locomotion. In the isolated CNS, GABA (10-5-10-4 M) strongly activated the feeding rhythm generator, excited the cerebral motoneurons innervating tentacle muscles (Ten MNs), and accelerated locomotor rhythm. A direct excitatory action of GABA (10-8 M) upon Ten MNs was demonstrated on isolated cells extracted from cerebral ganglia. It is concluded that GABA plays an important role in activation of various neuronal networks (organization of ‘functional synergy’) responsible for the consummatory stage of feeding behaviour. © Lippincott-Raven Publishers.