Original ArticlesCOVID-19 An Italian Hospital Response From the Nursing PerspectiveRolandi, Stefano RN, MScN; Villa, Giulia PhD, RN; D'Aloia, Pasqualino RN, MScN; Gengo, Valentina RN, CNS; Negro, Alessandra RN, CNS; Manara, Duilio Fiorenzo RNAuthor Information IRCCS San Raffaele Scientific Institute, Milan, Italy (Messrs Rolandi and D'Aloia, Dr Villa, and Mss Gengo and Negro); and Vita-Salute San Raffaele University, Milan, Italy (Mr Manara). Correspondence: Giulia Villa, PhD, RN, IRCCS San Raffaele Scientific Institute, Via Olgettina, 60, 20132, Milan, Italy ([email protected]). The authors would like to thank all the health care staff who participated in the emergency for their invaluable contribution. All the authors made a substantial contribution to the editing of the paper draft and met the 4 criteria for authorship recommended by the International Committee of Medical Journal Editors. S.R., G.V., and A.N. contributed to conception and design; S.R., G.V., V.G., and A.N. to drafting; and P.D.A. and D.F.M. to supervision. The authors declare no conflict of interest. Nursing Administration Quarterly: April/June 2021 - Volume 45 - Issue 2 - p 94-101 doi: 10.1097/NAQ.0000000000000467 Buy Metrics Abstract Novel coronavirus disease-2019 (COVID-19) is a new respiratory disease that has spread widely throughout the world. On February 20, 2020, the first Italian case of COVID-19 was reported. The infection rapidly spread across the country, and by August 11, 2020, a total of 250 566 official cases with 32 205 deaths (12.8%) were reported in Italy, counting a total of 96 884 positive cases and 16 833 deaths (17.3%) in the Lombardy region only. A huge demand to handle the COVID-19 outbreak challenged both the health care providers and the ordinary work in the hospital. From the beginning of the crisis, San Raffaele Scientific Institute, a 1318-bed tertiary care university hospital located in Lombardy, Northern Italy, has played a major role in supporting the national health care system for the treatment of COVID-19 cases, and a significant reorganization of the hospital was immediately required. The reorganization was carried out both structurally and with regard to the distribution of medical and nonmedical staff. This article aims to highlight the management strategies for the health care staff subsequent to the pandemic intense workload in San Raffaele Scientific Institute. © 2021 Wolters Kluwer Health, Inc. All rights reserved.