Original ArticlesComplexity Leadership Constructing 21st-Century Health CarePorter-O'Grady, Tim DM, EdD, APRN, FAAN, FAACWSAuthor Information Tim Porter-O'Grady Associates, Inc, and School of Nursing, Emory University, Atlanta, Georgia. Correspondence: Tim Porter-O'Grady, DM, EdD, APRN, FAAN, FAACWS, Tim Porter-O'Grady Associates, Inc, 195 14th St NE, Ste 509, Atlanta, GA 30309 (firstname.lastname@example.org). The author declares no conflict of interest. Nursing Administration Quarterly: April/June 2020 - Volume 44 - Issue 2 - p 92-100 doi: 10.1097/NAQ.0000000000000405 Buy Metrics Abstract In this 21st-century postdigital age, deeper and more relevant understandings of both structure and process are critical in laying the foundations for the success of human enterprises and systems for the foreseeable future. Leadership of these complex, networked initiatives and environments will require a fundamentally different understanding and tool sets essential to the well-designed, linked, and integrated undertaking of the human enterprise. This is no less true of the unfolding health care networks now becoming the substantive framework for the delivery of health care services in the foreseeable future. This article explicates the essentials of this new model for leadership. © 2020 Wolters Kluwer Health, Inc. All rights reserved.