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February 2020 - Volume 27 - Issue 2
pp: 123-250


Does preventive oophorectomy increase the risk of depression in BRCA mutation carriers?

Kotsopoulos, Joanne; Gronwald, Jacek; Lubinski, Jan; More

Menopause. 27(2):156-161, February 2020.


Invited Review





Creator: Paige Wynne
Video Production Specialist
Creative and Digital Services
University of Illinois at Chicago
Duration: 3:34
In this video, we glimpse the significance of Uterine fibroid disease and highlights their unusual persistence in menopause women. Moreover, we discuss the possible available treatment options as well as the advantages and disadvantages of using hormonal therapy in this specific population.
Creator: Elizabeth J. Pekas
Duration: 4:28
Menopause is often accompanied by an age-associated hormonal decline, elevated blood pressure, and poor body composition, and these negative effects on health have been shown to improve following exercise training. The Vascular Research Lab at the University of Nebraska at Omaha revealed for the first time that 12 weeks of resistance band exercise training restores the aging-related hormonal decline while improving blood pressure and body composition in postmenopausal women with stage 1 hypertension.
Creator: Benjamin S. Harris, MD, MPH
Duration: 2:49
The risks and benefits of hormone therapy in perimenopausal women have been extensively studied. Less is known about hormone therapy in breast or gynecologic cancer survivors and risk of cancer recurrence. We reviewed the available data to determine whether hormone therapy is safe for breast, ovarian, endometrial, and cervical cancer survivors. We also present a mechanism of reducing breast cancer incidence through estrogen-driven apoptosis pathways, and discuss the role of progestins in the growth of breast cancer stem cells. These concepts are a foundation for future research into the role of hormone replacement in treatment and prevention of breast cancer.
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