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Creator: Sussex Health Outcomes Research & Education in Cancer; filmed and edited by Matt Bemment, Communication Assistant, Brighton and Sussex Medical School
Duration: 4:35
What do we really know about sex after menopause? This video summary reports on the results of a free-text analysis on sexual activity in over 4,400 postmenopausal women who took part in UKCTOCS, a large UK ovarian cancer screening trial. It shows that sexuality can change when we get older and that relationship status and health have a direct effect on sexuality and satisfaction. We believe it is important to raise awareness among women and healthcare professionals to increase the understanding of sexual issues women may face in later life.
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Creator: Linda Besant
Duration: 5:47
The video introduces an article presenting data from 55 participants eligible for a randomized intervention study to treat moderate/severe postmenopausal dyspareunia. It discusses whether it deserves a broader explanation than that of atrophy. Participants described dyspareunia as “burning” and “raw.” GU examinations carefully checked for painful locations. Vulvar vestibule tenderness, rather than vaginal sensitivity, was the consistent physical finding. Liquid lidocaine could extinguish the pain. A neural phenomenon in the vestibule may be responsible for postmenopausal dyspareunia.
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Creator:
Duration: 5:16
This video is a summary of the manuscript titled ‘Metabolic effects of menopause: a cross-sectional characterization of body composition and exercise metabolism.’ The video discusses briefly the background, purpose, results, and conclusions of this study. Peri-menopause may be the optimal window for intervention, and these women should aim to prevent losses of fat-free mass and decrements in metabolism by participating in resistance and high-intensity exercise.
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Creator: Clinical Associate Professor Amanda Vincent, Monash Centre for Health Research and Implementation, Monash University, Melbourne Australia
Duration: 4:17
Early menopause, defined as menopause before age 45 years, affects up to 12% of women. This video summarizes a study evaluating the first co-designed digital resource (www.healthtalkaustralia.org) specifically for women with early menopause.
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Creator: Eleanor Donegan, Ph.D., C.Psych.
Duration: 3:03
The menopausal transition is associated with a number of adverse changes for many women, including vasomotor and depressive symptoms, anxiety, poor sleep, urogenital and sexual concerns. Pharmacotherapy is effective but can be associated with health-related concerns for some women and there is a need for non-pharmacological interventions that target a range of menopausal symptoms. Our research group developed a new cognitive behavioral therapy protocol (CBT-Meno) to target a range of commonly-reported menopausal symptoms. In this video, we summarize the results of a recent randomized controlled trial evaluating the effectiveness of the CBT-Meno protocol compared to a waitlist condition.
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Creator: Irwin Goldstein, MD
Duration: 3:48
This is a phase 3 pivotal trial of ospemifene versus placebo in women in menopause with moderate to severe vaginal dryness, a symptom of GSM. On physical examination, such women commonly have vulvar, vestibular and vaginal atrophy. This study, for the first time, utilized vulvar vestibular photography to objectively document changes in genital health. There were no changes noted in photography on placebo, however active therapy with a SERM resulted in regrowth of labia minora, normalization of the urethral gland prominence, resolution of the pallor and erythema of the vestibule and visualization of vestibular moisture. Visual assessment of genital health in such patients should be utilized in future trials.
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Creator: Shannon Laughlin-Tommaso
Duration:
In this video, we discuss how hysterectomy, even with ovarian conservation, increased the long-term risks of depression and anxiety by over 20% compared with referent women. In this population-based cohort with 20 years of follow-up, hysterectomy with ovarian conservation was associated an absolute risk increase of 7% for depression and 5% for anxiety. Women who had a hysterectomy before age 36 had even higher absolute risk increases: 12% for depression and 10% for anxiety.
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Creator: Nikoletta Mili
Duration: 6:03
Video summary of the article entitled “Genitourinary syndrome of menopause: A systematic review on prevalence and treatment”. This article aimed to systematically review the literature to investigate the prevalence of GSM and its treatment. GSM is a highly prevalent condition among women. Nevertheless, women are frequently not aware of its cause and its treatment options. The findings of this review underline the need for education of patients and health care professionals regarding GSM diagnosis and treatment options.
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Creator: Mankamal Kaur
Duration: 4:54
The video summarizes the statistical methods used and the major findings of the research article entitled ‘Is the cognitive performance of women sensitive to the severity of menopausal symptoms?’. The clinical implications of the current research has also been discussed in the video.
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Creator: Melanie Gibson-Helm
Duration: 4:01
In this video we describe a multiple-methods study to develop a Question Prompt List (QPL) for Early Menopause. The research resulted in a QPL for Early Menopause that is stakeholder informed, evidence-based, acceptable to women, and feasible to use in a clinic setting.
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Creator: Gayeong Kim
Duration: 6:07
The purpose of this study was to explore the associations of race/ethnicity and menopausal status to gastrointestinal (GI) symptoms experienced during the menopausal transition while considering multiple factors that could influence the symptoms.
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Creator: No sponsor
Created by Mayo Clinic
Duration: 4:22
The video reviews the findings from our paper entitled “Associations of Pituitary-Ovarian Hormones and White Matter Hyperintensities in Recently Menopausal Women using Hormone Therapy.” In recently menopausal women participating in the Kronos Early Estrogen Prevention Study (KEEPS), greater increases in estrone associated with smaller increases in WMH volume in both the transdermal estradiol and oral conjugated equine estrogen groups. In addition, greater decreases in FSH associated with smaller increases in WMH volume over time but only in women using the transdermal estrogen. Our results demonstrate that the type of hormone therapy used during menopause contributes to different levels of circulating hormones which then may have different impact on brain structure during treatment.
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Creator: Jiwon Lee, PhD
Duration: 4:01
This study used a structural equation model to test the significance of factors associated with the psychological well-being of midlife women in South Korea based on the transactional model of stress and coping. Self-efficacy (exogenous variable) was positively associated with the psychological well-being (endogenous variable) of middle-aged women and appeared to be mediated by perceived stress, menopausal management, menopausal symptoms, and self-compassion. The predictor variables had an explanatory power of 79.5% for psychological well-being. These results can be helpful in the future development of interventions to improve psychological well-being by improving self-efficacy and coping with stress in middle-aged women.
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Creator: Christina Dancz, MD
Duration: 2:54
In this video abstract, Dr. Christina Dancz from the Keck School of Medicine of the University of Southern California (USC) comments on the role of sex steroid hormones in pelvic organ prolapse. More specifically, she introduces the viewer to the effects of estrogen and progestin on ligament strength, tissue remodeling, the extracellular matrix, and clinical presentation. Taken altogether, these findings suggest that there may be a role for the exogenous administration of hormones in the prevention of pelvic organ prolapse. This topic is more fully explored in our published review in Menopause.
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Creator: Mithra Pharmaceuticals (sponsor)
Duration: 4:29
This video summarizes the results of a study to select the minimum effective dose of estetrol (E4) for the treatment of postmenopausal women with vasomotor symptoms (VMS, hot flushes). The reduction in frequency and severity of VMS was most pronounced for 15 mg E4, and was significant at week 4 and 12. E4 was well tolerated and there were no unexpected adverse events. It was concluded that oral E4 15 mg is the minimum effective daily oral dose for treatment of VMS.
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Creator: Kazue Nagai
Duration: 5:21
Symptoms of urinary incontinence (e.g., stress urinary incontinence [SUI]) are relatively common in women. Furthermore, overactive bladder (OAB) syndrome occurs in approximately 10% of women. Symptoms of these conditions affect health-related quality of life. Therefore, a better understanding of the prevalence and associated factors of these urinary symptoms is required for improving and preventing these symptoms. This study investigated the prevalence and factors associated with urinary symptoms using cross-sectional data from the Japan Nurses’ Health Study in 12,198 women. The prevalence of OAB was 9.5%, that of SUI was 13.9%, and that of mixed urinary incontinence was 2.1%. Age 45-54 years and postmenopausal status was significantly associated with OAB, and age group (45–49 and 50–54 years), body mass index, and parous status were significantly associated with the risk of SUI.
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Creator: Alison Shea
Duration: 5:07
The menopause transition is a vulnerable time for mental health and it is important to better understand the risk factors for depression during this time. This study using baseline data from the Canadian Longitudinal Study on Aging shows that premature menopause and the use of hormone therapy, as well as low education, low household income, living alone, being nulliparous, and having low social support are associated with current depression measured using the Center for Epidemiologic studies Short Depression Scale.
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Creator: Akira Taguchi
Duration: 4:23
Bisphosphonate is the first line agent for osteoporosis, although We have been worried about the occurrence of severe adverse event associated with bisphosphonate on oral cavity, osteonecrosis of the jaws (ONJ). Also, periodontal disease, especially is the important risk factor for ONJ. The aim of this study was to determine whether once-yearly zoledronic acid in combination with proper self-oral hygiene management can improve symptomatic periodontal disease compared with placebo. Our results suggest that bisphosphonate use in combination of proper self-oral hygiene management for osteoporosis patients can prevent symptomatic periodontal disease, resulting in the risk reduction of bisphosphonate-related ONJ.
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Creator: Fatima Cody Stanford, MD, MPH, MPA
Duration: 5:25
This video explains how weight promoting medications may lead to weight gain in women during menopause. It should be noted that hormonal changes associated with menopause already lead to weight gain. However, weight gain may be exacerbated with the use of several commonly prescribed medications.
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Creator: Physicians Committee for Responsible Medicine
Duration: 04:44
Author of the Women’s Study for the Alleviation of Vasomotor Symptoms (WAVS), Neal Barnard, MD, FACC, and WAVS study participants, discuss how eating a plant-based diet, which includes soybeans, can reduce the severity and frequency of hot flashes.
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Creator: Jennie Mastroianni, DNP
Duration: 5:18
Genitourinary syndrome of menopause (GSM) affects nearly 50% of postmenopausal women. Yet, it is a problem that is difficult for both providers and patients to discuss—particularly the impact of GSM symptoms on a women’s daily activities. This quality improvement project implemented the Day-to-Day Impact of Vaginal Aging (DIVA) questionnaire to improve the identification and diagnosis of GSM. Our findings support the use of the DIVA questionnaire as an efficient tool in a busy women’s health practice setting to facilitate GSM identification and diagnosis.
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Creator:
Duration: 4:52
Dr. Juliana Kling, first author, describes a summary of findings from their manuscript “Associations of Sleep and Female Sexual Function: Good Sleep Quality Matters.” The evaluated potential associations between sleep (quality and duration) and sexual function using validated tools after accounting for factors that may influence both outcomes. Overall, poor sleep quality was associated with a greater risk for Female Sexual Dysfunction. While shorter sleep duration correlated with a greater risk for FSD on univariate analysis, this finding appears to be moderated by other factors known to associate with both short sleep duration and FSD. Conversely, good sleep quality was associated with sexual activity. Therefore, this study shows that sleep quality appears to be linked to female sexual function and sexual activity. In addition to its myriad effects on health, poor sleep quality may be independently associated with FSD.
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Creator: Robin Seitzman, PhD, MPH
Duration:
Overview of a study to assess the effect of a web-based educational intervention on women’s healthcare provider knowledge of breast density, its risk and screening implications, and comfort level in discussing these topics with patients.
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Creator: Paige Wynne
Video Production Specialist
Creative and Digital Services
University of Illinois at Chicago
Duration: 3:34
In this video, we glimpse the significance of Uterine fibroid disease and highlights their unusual persistence in menopause women. Moreover, we discuss the possible available treatment options as well as the advantages and disadvantages of using hormonal therapy in this specific population.
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