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Hot Flashes, Memory and Brain Function

Video Author: Pauline Maki
Published on: 02.20.2020
Associated with: Menopause. 27(3):269-277, March 2020

This video describes results from a recent study examining the association between physiologic hot flashes and brain function as women learn and remember words.

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The Vaginal Laser Therapy versus Vaginal Estrogen Therapy: The VeLVET Trial

2:49

Why study pelvic floor disorders in women with premature ovarian insufficiency?

4:22

Safety of Vaginal Estrogens: A Recap of a Systematic Review

4:34

Are women still sexually active after menopause?

4:35

Hot Flashes, Memory and Brain Function

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33 Videos

Gabapentin for the treatment of hot flushes in menopause: A meta-analysis

Creator: Chulmin Lee

Duration: 3:18

Gabapentin is a plausible option for treating hot flush in menopause, especially when hormone therapy is contraindicated. This meta-analysis including 7 papers shows gabapentin reduces frequency, duration and intensity of vasomotor symptoms. Side effects such as dizziness and somnolence are tolerable.

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Mental well-being and menopause

Creator: Dmitriy Bondarev

Duration: 4:32

Mental well-being and menopause

Play Video | + Favorites

Why study pelvic floor disorders in women with premature ovarian insufficiency?

Creator: Luiz Gustavo Oliveira Brito

Duration: 4:22

This video explains the reasons for performing this study and the main findings when we compared women with premature ovarian insufficiency versus a control group with regard to pelvic floor disorders.

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Association between common mental disorders, sleep quality and menopausal symptoms: A population-based study in Southern Brazil

Creator: Agnes Ludwig Neutzling

Duration: 4:43

This is a resume of principal aspects of the article named “Association between common mental disorders, sleep quality and menopausal symptoms: A population-based study in Southern Brazil”.

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Interaction between postmenopausal hormone therapy and diabetes on cataract.

Creator: Christy Costanian

Duration: 3:36

The purpose of this study was to investigate whether postmenopausal hormone therapy (HT) use interacts with diabetes, a risk factor for several age-related eye diseases. The study found that long-term HT use and type 2 diabetes interact in their relationship with cataract such that the odds of cataract is highest in that group.

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Causes of low libido in postmenopausal women

Creator: Holly Thomas

Duration: 2:44

Dr. Holly Thomas, Associate Professor of Medicinefrom the University of Pittsburgh describes herresearch, in which she conducted interviews andfocus groups with women aged 60 and older toidentify causes of low libido. Postmenopausalvaginal symptoms, erectile dysfunction in malepartners, and life stressors were identified as majorcontributors. She ends with recommendations forhealthcare providers.

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Safety of Vaginal Estrogens: A Recap of a Systematic Review

Creator: Carolyn J. Crandall, MD, MS

Duration: 4:34

In this video, Dr. Carolyn J. Crandall describes the key findings and clinical “take-home messages” of the systematic review regarding safety of vaginal estrogens that her team recently performed.

Play Video | + Favorites

Is there any association between menopause and sleep disorders?

Creator: Sheida Zolfaghari

Duration: 1:36

Sleep disturbances are among the important problems that involve women after menopause. Despite of several studies about the relationship between menopause and sleep, there are still some controversies. In this study with a large sample size on the Canadian population, we studied different types of sleep disorders. Our findings revealed that menopause is associated with sleep onset insomnia disorder and obstructive sleep apnea. But we were not able to find an association between menopause and sleep maintenance insomnia disorder, daytime somnolence, rapid eye movement sleep behavior disorder and restless leg syndrome.

Play Video | + Favorites

Hot Flashes, Memory and Brain Function

Creator: Pauline Maki

Duration: 3:31

This video describes results from a recent study examining the association between physiologic hot flashes and brain function as women learn and remember words.

Play Video | + Favorites

“Hormonal management of menopausal symptoms in women with a history of gynecologic malignancy”

Creator: Benjamin S. Harris, MD, MPH

Duration: 2:49

The risks and benefits of hormone therapy in perimenopausal women have been extensively studied. Less is known about hormone therapy in breast or gynecologic cancer survivors and risk of cancer recurrence. We reviewed the available data to determine whether hormone therapy is safe for breast, ovarian, endometrial, and cervical cancer survivors. We also present a mechanism of reducing breast cancer incidence through estrogen-driven apoptosis pathways, and discuss the role of progestins in the growth of breast cancer stem cells. These concepts are a foundation for future research into the role of hormone replacement in treatment and prevention of breast cancer.

Play Video | + Favorites

Aging-Related Hormonal Decline in Postmenopausal Women Improved with Resistance Exercise Training

Creator: Elizabeth J. Pekas

Duration: 4:28

Menopause is often accompanied by an age-associated hormonal decline, elevated blood pressure, and poor body composition, and these negative effects on health have been shown to improve following exercise training. The Vascular Research Lab at the University of Nebraska at Omaha revealed for the first time that 12 weeks of resistance band exercise training restores the aging-related hormonal decline while improving blood pressure and body composition in postmenopausal women with stage 1 hypertension.

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Uterine Fibroids in Menopause and Perimenopause

Creator: Paige Wynne
Video Production Specialist
Creative and Digital Services
University of Illinois at Chicago

Duration: 3:34

In this video, we glimpse the significance of Uterine fibroid disease and highlights their unusual persistence in menopause women. Moreover, we discuss the possible available treatment options as well as the advantages and disadvantages of using hormonal therapy in this specific population.

Play Video | + Favorites

A Question Prompt List for Early Menopause

Creator: Melanie Gibson-Helm

Duration: 4:01

In this video we describe a multiple-methods study to develop a Question Prompt List (QPL) for Early Menopause. The research resulted in a QPL for Early Menopause that is stakeholder informed, evidence-based, acceptable to women, and feasible to use in a clinic setting.

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Investigating resident retention of menopause-related knowledge after completion of learning modules

Creator: Julia Shinnick

Duration: 1:30

Obstetrics and Gynecology and Family Medicine Resident retention of menopause-related knowledge after completion of PowerPoint learning modules tailored to learning styles.

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What do healthcare professionals and high-risk women need to know about risk-reducing salpingo-oophorectomy?

Creator: Martha Hickey

Duration: 6:46

What do healthcare professionals and high-risk women need to know about risk-reducing salpingo-oophorectomy?

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The Seasonal Effects on Menopause Symptoms

Creator: Brian Lillie

Duration: 4:10

Sioban Harlow, professor of epidemiology and global public health and director of the Center for Midlife Science at the University of Michigan School of Public Health, explains findings from a study published in the July 2019 issue of the journal Menopause on the impact of season and proximity to the final menstrual period on common menopausal symptoms, including hot flashes, night sweats and trouble sleeping.

Play Video | + Favorites

The Vaginal Laser Therapy versus Vaginal Estrogen Therapy: The VeLVET Trial

Creator: David Rogant, Cleveland Clinic

Duration: 2:49

This video presents our impetus to embark on this randomized trial and the significance of our manuscript. We discuss the innovative use of CO2 fractional laser therapy for the treatment of genitourinary syndrome of menopause (GSM) and compare it to gold standard therapy. We summarize our thoughts regarding clinical applicability of the CO2 fractional laser for GSM and make our recommendations for future work in studying its long-term efficacy and safety.

Play Video | + Favorites

Hysterectomy and its association with Mental Health

Creator: Shannon Laughlin-Tommaso

Duration:

In this video, we discuss how hysterectomy, even with ovarian conservation, increased the long-term risks of depression and anxiety by over 20% compared with referent women. In this population-based cohort with 20 years of follow-up, hysterectomy with ovarian conservation was associated an absolute risk increase of 7% for depression and 5% for anxiety. Women who had a hysterectomy before age 36 had even higher absolute risk increases: 12% for depression and 10% for anxiety.

Play Video | + Favorites

Statin Therapy in Women: how effective and safe is it?

Creator: Taryn Offenbacher

Duration: 3:11

The video provides an introduction to a review article in the journal regarding the evidence about effectiveness and safety of statin therapy in women.

Play Video | + Favorites

Mental health before bilateral oophorectomy

Creator: Timothy Seelinger, Mayo Clinic Media Support Services

Duration: 6:18

The first part of the video provides details about the methods, the time frame, and the study population, and briefly summarizes the principal findings from our study.The second part of the video, discusses the clinical context of the findings. In particular, it describes the itinerary of women transitioning from mental health symptoms and problems to gynecological symptoms, from gynecological symptoms to primary care attention, and from primary care attention to gynecological surgery. This part also addresses possible alternative clinical strategies for the future.The third part of the video provides some simple conclusions and recommendations.

Play Video | + Favorites

Gabapentin for the treatment of hot flushes in menopause: A meta-analysis

Creator: Chulmin Lee

Duration: 3:18

Gabapentin is a plausible option for treating hot flush in menopause, especially when hormone therapy is contraindicated. This meta-analysis including 7 papers shows gabapentin reduces frequency, duration and intensity of vasomotor symptoms. Side effects such as dizziness and somnolence are tolerable.

Play Video | + Favorites

Mental well-being and menopause

Creator: Dmitriy Bondarev

Duration: 4:32

Mental well-being and menopause

Play Video | + Favorites

Why study pelvic floor disorders in women with premature ovarian insufficiency?

Creator: Luiz Gustavo Oliveira Brito

Duration: 4:22

This video explains the reasons for performing this study and the main findings when we compared women with premature ovarian insufficiency versus a control group with regard to pelvic floor disorders.

Play Video | + Favorites

Interaction between postmenopausal hormone therapy and diabetes on cataract.

Creator: Christy Costanian

Duration: 3:36

The purpose of this study was to investigate whether postmenopausal hormone therapy (HT) use interacts with diabetes, a risk factor for several age-related eye diseases. The study found that long-term HT use and type 2 diabetes interact in their relationship with cataract such that the odds of cataract is highest in that group.

Play Video | + Favorites

Causes of low libido in postmenopausal women

Creator: Holly Thomas

Duration: 2:44

Dr. Holly Thomas, Associate Professor of Medicinefrom the University of Pittsburgh describes herresearch, in which she conducted interviews andfocus groups with women aged 60 and older toidentify causes of low libido. Postmenopausalvaginal symptoms, erectile dysfunction in malepartners, and life stressors were identified as majorcontributors. She ends with recommendations forhealthcare providers.

Play Video | + Favorites

Safety of Vaginal Estrogens: A Recap of a Systematic Review

Creator: Carolyn J. Crandall, MD, MS

Duration: 4:34

In this video, Dr. Carolyn J. Crandall describes the key findings and clinical “take-home messages” of the systematic review regarding safety of vaginal estrogens that her team recently performed.

Play Video | + Favorites

Is there any association between menopause and sleep disorders?

Creator: Sheida Zolfaghari

Duration: 1:36

Sleep disturbances are among the important problems that involve women after menopause. Despite of several studies about the relationship between menopause and sleep, there are still some controversies. In this study with a large sample size on the Canadian population, we studied different types of sleep disorders. Our findings revealed that menopause is associated with sleep onset insomnia disorder and obstructive sleep apnea. But we were not able to find an association between menopause and sleep maintenance insomnia disorder, daytime somnolence, rapid eye movement sleep behavior disorder and restless leg syndrome.

Play Video | + Favorites

Hot Flashes, Memory and Brain Function

Creator: Pauline Maki

Duration: 3:31

This video describes results from a recent study examining the association between physiologic hot flashes and brain function as women learn and remember words.

Play Video | + Favorites

“Hormonal management of menopausal symptoms in women with a history of gynecologic malignancy”

Creator: Benjamin S. Harris, MD, MPH

Duration: 2:49

The risks and benefits of hormone therapy in perimenopausal women have been extensively studied. Less is known about hormone therapy in breast or gynecologic cancer survivors and risk of cancer recurrence. We reviewed the available data to determine whether hormone therapy is safe for breast, ovarian, endometrial, and cervical cancer survivors. We also present a mechanism of reducing breast cancer incidence through estrogen-driven apoptosis pathways, and discuss the role of progestins in the growth of breast cancer stem cells. These concepts are a foundation for future research into the role of hormone replacement in treatment and prevention of breast cancer.

Play Video | + Favorites

Aging-Related Hormonal Decline in Postmenopausal Women Improved with Resistance Exercise Training

Creator: Elizabeth J. Pekas

Duration: 4:28

Menopause is often accompanied by an age-associated hormonal decline, elevated blood pressure, and poor body composition, and these negative effects on health have been shown to improve following exercise training. The Vascular Research Lab at the University of Nebraska at Omaha revealed for the first time that 12 weeks of resistance band exercise training restores the aging-related hormonal decline while improving blood pressure and body composition in postmenopausal women with stage 1 hypertension.

Play Video | + Favorites

Uterine Fibroids in Menopause and Perimenopause

Creator: Paige Wynne
Video Production Specialist
Creative and Digital Services
University of Illinois at Chicago

Duration: 3:34

In this video, we glimpse the significance of Uterine fibroid disease and highlights their unusual persistence in menopause women. Moreover, we discuss the possible available treatment options as well as the advantages and disadvantages of using hormonal therapy in this specific population.

Play Video | + Favorites

A Question Prompt List for Early Menopause

Creator: Melanie Gibson-Helm

Duration: 4:01

In this video we describe a multiple-methods study to develop a Question Prompt List (QPL) for Early Menopause. The research resulted in a QPL for Early Menopause that is stakeholder informed, evidence-based, acceptable to women, and feasible to use in a clinic setting.

Play Video | + Favorites

Investigating resident retention of menopause-related knowledge after completion of learning modules

Creator: Julia Shinnick

Duration: 1:30

Obstetrics and Gynecology and Family Medicine Resident retention of menopause-related knowledge after completion of PowerPoint learning modules tailored to learning styles.

Play Video | + Favorites

What do healthcare professionals and high-risk women need to know about risk-reducing salpingo-oophorectomy?

Creator: Martha Hickey

Duration: 6:46

What do healthcare professionals and high-risk women need to know about risk-reducing salpingo-oophorectomy?

Play Video | + Favorites

The Seasonal Effects on Menopause Symptoms

Creator: Brian Lillie

Duration: 4:10

Sioban Harlow, professor of epidemiology and global public health and director of the Center for Midlife Science at the University of Michigan School of Public Health, explains findings from a study published in the July 2019 issue of the journal Menopause on the impact of season and proximity to the final menstrual period on common menopausal symptoms, including hot flashes, night sweats and trouble sleeping.

Play Video | + Favorites

The Vaginal Laser Therapy versus Vaginal Estrogen Therapy: The VeLVET Trial

Creator: David Rogant, Cleveland Clinic

Duration: 2:49

This video presents our impetus to embark on this randomized trial and the significance of our manuscript. We discuss the innovative use of CO2 fractional laser therapy for the treatment of genitourinary syndrome of menopause (GSM) and compare it to gold standard therapy. We summarize our thoughts regarding clinical applicability of the CO2 fractional laser for GSM and make our recommendations for future work in studying its long-term efficacy and safety.

Play Video | + Favorites

Hysterectomy and its association with Mental Health

Creator: Shannon Laughlin-Tommaso

Duration:

In this video, we discuss how hysterectomy, even with ovarian conservation, increased the long-term risks of depression and anxiety by over 20% compared with referent women. In this population-based cohort with 20 years of follow-up, hysterectomy with ovarian conservation was associated an absolute risk increase of 7% for depression and 5% for anxiety. Women who had a hysterectomy before age 36 had even higher absolute risk increases: 12% for depression and 10% for anxiety.

Play Video | + Favorites

Statin Therapy in Women: how effective and safe is it?

Creator: Taryn Offenbacher

Duration: 3:11

The video provides an introduction to a review article in the journal regarding the evidence about effectiveness and safety of statin therapy in women.

Play Video | + Favorites

Mental health before bilateral oophorectomy

Creator: Timothy Seelinger, Mayo Clinic Media Support Services

Duration: 6:18

The first part of the video provides details about the methods, the time frame, and the study population, and briefly summarizes the principal findings from our study.The second part of the video, discusses the clinical context of the findings. In particular, it describes the itinerary of women transitioning from mental health symptoms and problems to gynecological symptoms, from gynecological symptoms to primary care attention, and from primary care attention to gynecological surgery. This part also addresses possible alternative clinical strategies for the future.The third part of the video provides some simple conclusions and recommendations.

Play Video | + Favorites

Introduction to a comprehensive health risk prediction tool for post-menopausal women

Creator: John Robbins and Haley Hedlin

Duration: 4:16

The authors describe the motivation behind the comprehensive health risk prediction tool for post-menopausal women and its significance. An introduction to the tool’s implementation in a web-based calculator is also provided. The comprehensive health risk prediction tool using competing risks models to predict the probability of a woman experiencing myocardial infarction, stroke, lung cancer, breast cancer, colorectal cancer, hip fracture, or death within 5, 10, and 15 years.

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Exercise and physical function in postmenopausal women

Creator: Paulo Ricardo Prado Nunes

Duration: 03:26

- The exercise guidelines recommend 150 minutes/week of combined training (CT), aerobic and resistance exercises, for improvements in body composition (BC), muscle strength (MS) and physical function (PF). However, the lack of time and access to physical training facilities are commons barriers for people not to comply with the exercise guidelines.

- The high-intensity interval training (60 minutes/week - HIIT) is an exercise strategy to overcome the time commitment problem. However, there is no evidence regarding the HIIT effects on MS and PF.

- This study compared the effects of HIIT with CT on PF, BC and MS in obese postmenopausal women.

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The importance of central obesity in postmenopausal women with obstructive coronary artery disease

Creator: Jun Hwan Cho

Duration: 4:34

Central obesity is an independent factor for obstructive coronary artery disease in postmenopausal women. The importance of the assessment of central obesity rather than overall obesity in postmenopausal women for better risk stratification and therapeutic consideration of coronary artery disease.

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Genetic Associations with Age of Menopause in Familial Longevity

Creator: Harold Bae

Duration: 3:02

This video provides significance and motivations for the current work, which is a genome-wide association study of age of menopause in a sample enriched for longevity (the Long Life Family Study and Health and Retirement Study). Contrary to previously published results that focused on age of menopause in the general population, our analysis looked at age of menopause in a population enriched for longevity. Therefore, some novel associations may be specifically linked to healthy aging and longer survival.

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Are women still sexually active after menopause?

Creator: Sussex Health Outcomes Research & Education in Cancer; filmed and edited by Matt Bemment, Communication Assistant, Brighton and Sussex Medical School

Duration: 4:35

What do we really know about sex after menopause? This video summary reports on the results of a free-text analysis on sexual activity in over 4,400 postmenopausal women who took part in UKCTOCS, a large UK ovarian cancer screening trial. It shows that sexuality can change when we get older and that relationship status and health have a direct effect on sexuality and satisfaction. We believe it is important to raise awareness among women and healthcare professionals to increase the understanding of sexual issues women may face in later life.

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MATE Survey video

Creator: Sharon J Parish

Duration: 3:22

This video is the author's summary of the Men's Perceptions and Attitudes Towards Menopause (MATE) survey, which is one of the first large studies surveying male partners of menopausal women. These men provided valuable insight into the impact of menopause on them and their partners, and revealed that most men discuss symptoms and are influential in helping their partners select treatments. Results support expanding patient education to include the male partners of menopausal women, who communicate with their partners about symptoms, may be influential in fostering lifestyle changes, and participate in decision-making regarding treatment.

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MUSCLE STRENGTH & DEPRESSION /ANXIETY

Creator: EU LEONG YONG

Duration: 5:00

Despite the large burden of due to depression/anxiety, few studies have examined the risk factors of depression and anxiety, especially in a multiethnic Asians. This study shows that of the multiple risks factors for depression and/or anxiety, objectively measures of physical performance such as hand grip strength and lower body strength increases risk of depression and anxiety in mid-life Asian women. Exercises to improve muscle strength may reduce risks of depression and/or anxiety.

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Visual Assessment of Genital Health in Menopausal Women

Creator: Irwin Goldstein, MD

Duration: 3:48

This is a phase 3 pivotal trial of ospemifene versus placebo in women in menopause with moderate to severe vaginal dryness, a symptom of GSM. On physical examination, such women commonly have vulvar, vestibular and vaginal atrophy. This study, for the first time, utilized vulvar vestibular photography to objectively document changes in genital health. There were no changes noted in photography on placebo, however active therapy with a SERM resulted in regrowth of labia minora, normalization of the urethral gland prominence, resolution of the pallor and erythema of the vestibule and visualization of vestibular moisture. Visual assessment of genital health in such patients should be utilized in future trials.

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Concerns about compounded hormonal preparations

Creator: Frank Stanczyk

Duration: 5:28

Hormone preparations such as topical progesterone creams and oral progesterone capsules are used by many postmenopausal women using estrogens to prevent endometrial hyperhidrosis. These preparations are prepared from compounding pharmacies, which are not regulated by the FDA. Our study showed significant variability in estradiol and progesterone doses in capsules, and somewhat less in creams, obtained from 13 different compounding pharmacies. In addition, there is uncertainty regarding whether or not progesterone capsules and creams protect the endometrium. These findings should be concerning to postmenopausal women using compounded hormonal preparations, which warrant regulation by the FDA.

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Validation of the CBT-Meno Protocol: A summary of a recent RCT

Creator: Eleanor Donegan, Ph.D., C.Psych.

Duration: 3:03

The menopausal transition is associated with a number of adverse changes for many women, including vasomotor and depressive symptoms, anxiety, poor sleep, urogenital and sexual concerns. Pharmacotherapy is effective but can be associated with health-related concerns for some women and there is a need for non-pharmacological interventions that target a range of menopausal symptoms. Our research group developed a new cognitive behavioral therapy protocol (CBT-Meno) to target a range of commonly-reported menopausal symptoms. In this video, we summarize the results of a recent randomized controlled trial evaluating the effectiveness of the CBT-Meno protocol compared to a waitlist condition.

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