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Modification of Blood Pressure during the Administration of Phytoestrogens, Acupuncture or Hormones for the treatment of Climacteric Symptoms

Video Author: Angelo Cagnacci
Published on: 08.14.2020

This video describes a difference in blood pressure modification during the administration of phytoestrogens, acupuncture or hormones for the treatment of climacteric symptoms. Blood pressure decreases during phytoestrogens or acupuncture but not hormones administration. Possible mechanisms and implications are discussed.

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Creator: Angelo Cagnacci
Duration: 4:32
This video describes a difference in blood pressure modification during the administration of phytoestrogens, acupuncture or hormones for the treatment of climacteric symptoms. Blood pressure decreases during phytoestrogens or acupuncture but not hormones administration. Possible mechanisms and implications are discussed.
Creator: Fundacion Dexeus Mujer
Duration: 2:28
The overall prevalence of ocular surface symptoms was 64%. It was more prevalent and more severe in postmenopausal women, whit a significant differences regarding premenopausal women. Our study found that early age at menopause was significantly associated with an increased risk of ocular surface disease symptoms.
Creator: Dr Marija Glisic
Duration: 3:40
Brief summary of rationale and most important findings.
Creator: Department of Obstetrics & Gynecology, University of Chicago
Duration: 3:41
Dr. Monica Christmas discusses her research with the international COMMA consortium. Through COMMA, clinicians and researchers with expertise in the field of menopause, along with industry and consumers, are working together to develop Core Outcome Sets for vasomotor and genitourinary symptoms at menopause. In this video, Dr. Christmas, shares findings from a systematic review of outcomes and measurement tools reported in randomized clinical trials of interventions for genitourinary symptoms associated with menopause.
Creator: E. Armeni
Duration: 3:51
Retinol binding protein 4; menopause; arterial stiffness; cardiovascular disease
Creator: Mithra Pharmaceuticals (sponsor)
Duration: 4:29
This video summarizes the results of a study to select the minimum effective dose of estetrol (E4) for the treatment of postmenopausal women with vasomotor symptoms (VMS, hot flushes). The reduction in frequency and severity of VMS was most pronounced for 15 mg E4, and was significant at week 4 and 12. E4 was well tolerated and there were no unexpected adverse events. It was concluded that oral E4 15 mg is the minimum effective daily oral dose for treatment of VMS.
Creator: Beate Sydora
Duration: 5:01
The video highlights the significance of assessing the therapeutic value of walking exercise programs for women in menopause transition and postmenopausal. Though the health benefits of exercise are well known, menopausal women are often reluctant to exercise. Walking represents fewer barriers for women in midlife as it is inexpensive, easily accessible, and has low risk of injury. Sustained walking could serve as an alternative to hormone therapy or as a beneficial addition to hormone therapy or pharmaceutical drugs. The video hints to the findings of the scoping review designed to explore the current literature on the therapeutic effect of walking programs on menopause-related symptoms and risk factors. Limitations are discussed as well as suggestions for future research.
Creator: Christina Dancz, MD
Duration: 2:54
In this video abstract, Dr. Christina Dancz from the Keck School of Medicine of the University of Southern California (USC) comments on the role of sex steroid hormones in pelvic organ prolapse. More specifically, she introduces the viewer to the effects of estrogen and progestin on ligament strength, tissue remodeling, the extracellular matrix, and clinical presentation. Taken altogether, these findings suggest that there may be a role for the exogenous administration of hormones in the prevention of pelvic organ prolapse. This topic is more fully explored in our published review in Menopause.
Creator: No sponsor
Created by Mayo Clinic
Duration: 4:22
The video reviews the findings from our paper entitled “Associations of Pituitary-Ovarian Hormones and White Matter Hyperintensities in Recently Menopausal Women using Hormone Therapy.” In recently menopausal women participating in the Kronos Early Estrogen Prevention Study (KEEPS), greater increases in estrone associated with smaller increases in WMH volume in both the transdermal estradiol and oral conjugated equine estrogen groups. In addition, greater decreases in FSH associated with smaller increases in WMH volume over time but only in women using the transdermal estrogen. Our results demonstrate that the type of hormone therapy used during menopause contributes to different levels of circulating hormones which then may have different impact on brain structure during treatment.
Creator: Purim Ruanphoo, MD.
Duration: 3:06
Introduction to the RCT of vaginal CO2 laser and sham procedure in treating vaginal atrophy.
Creator: CU-Anschutz Medical Campus, Office of Communications (contact Kristen O’Neill)
Duration: 1:51
C. Neill Epperson, MD, Chair and Robert Freedman Endowed Professor of Psychiatry at the University of Colorado-Anschutz Medical Campus highlights the significance of their study focusing on subjective and objective executive function difficulties after surgical menopause. While negative mood states (anxiety/depression) are common among individuals who endorse adverse childhood experiences (ACEs), these symptoms did not fully explain the relationship between ACEs and subjective executive function complaints or performance on working memory and sustained attention tasks. These data suggest that ACEs exert an enduring negative impact on cognition among women who experience new-onset executive function complaints after RRSO.
Creator: James Smith
Duration: 1:56
This video briefly raises the question of whether climate change will increase the incidence of menopausal hot flashes as raised in our related commentary. It challenges readers to consider what they can do to help us understand this more and prepare for these potential impacts.
Creator: Michael Shikany
Duration: 5:16
This video provides a brief overview of the Menopause manuscript, Associations of Social, Physical, and Financial Factors with Diet Quality Among Older, Community-dwelling Women
Creator: Alison Shea
Duration: 5:07
The menopause transition is a vulnerable time for mental health and it is important to better understand the risk factors for depression during this time. This study using baseline data from the Canadian Longitudinal Study on Aging shows that premature menopause and the use of hormone therapy, as well as low education, low household income, living alone, being nulliparous, and having low social support are associated with current depression measured using the Center for Epidemiologic studies Short Depression Scale.
Creator: Bence Kozma MD PhD / No Sponsor
Duration: 3:15
Many studies suggest that zinc levels may correlate with some vaginal conditions, but the role in the diagnosis of Genitourinary syndrome of Menopause or Vulvovaginal Atrophy is not known. Cervicovaginal lavage has been widely used to investigate changes in the vagina. In our prospective cohort study the multivariate regression model revealed a significant association between vaginal atrophy and cervicovaginal lavage zinc levels. Measuring the amount of zinc in cervicovaginal lavage could aid in the diagnosis of Genitourinary syndrome of Menopause. Zinc levels of cervicovaginal lavage could be used as a new marker of vaginal atrophy.
Creator: Hyun-Jin Kim
Duration: 3:19
Marriage is an important social factor that can provide protection against harmful health outcomes. There may be sex differences in the response to stress from a without spouse status. Clinicians should consider their marital status to predict subsequent cardiovascular disease.
Creator: Dr Nadav Michaan
Duration: 3:13
This video summarizes our work regarding the accuracy of ascites fluid in the diagnosis of ovarian cancer among post-menopausal patients (accuracy, sensitivity, specificity, negative and positive predictive values)
Creator: Dostogir Harun with the help of Dr. Mahfuj Alam
Duration: 2:52
This video is the summary of the article entitled ‘Knowledge and associated attitudes with menopause among women aged 45-60 years: A pilot study among rural and urban women in Bangladesh’. Happy to accept HTML if sponsor wants to place a logo or image file.
Creator:
Duration: 2:35
Prof. Angelica Linden Hirschberg describes main aspects of the Blissafe Study, a European multinational investigation conducted in collaboration with clinical oncologists and gynecologists, and underlines the clinical relevance of the results. Ultra-low-dose 0.005% estriol vaginal gel has demonstrated efficacy over severe vulvovaginal symptoms experienced by women with breast cancer, while no relevant increase of plasmatic estrogens or variation of hypophyseal hormones is observed after treatment.
Creator: Creator: Rowan University Clinical Health And Social Experiences (CHASE) research team
Duration: 4:53
Detailed description of new research demonstrating that different quantification methods for measuring midlife women’s physical activity produce meaningfully different conclusions about activity engagement in this population.



Creator: E. Armeni
Duration: 3:51
Retinol binding protein 4; menopause; arterial stiffness; cardiovascular disease
Creator: Mithra Pharmaceuticals (sponsor)
Duration: 4:29
This video summarizes the results of a study to select the minimum effective dose of estetrol (E4) for the treatment of postmenopausal women with vasomotor symptoms (VMS, hot flushes). The reduction in frequency and severity of VMS was most pronounced for 15 mg E4, and was significant at week 4 and 12. E4 was well tolerated and there were no unexpected adverse events. It was concluded that oral E4 15 mg is the minimum effective daily oral dose for treatment of VMS.
Creator: Beate Sydora
Duration: 5:01
The video highlights the significance of assessing the therapeutic value of walking exercise programs for women in menopause transition and postmenopausal. Though the health benefits of exercise are well known, menopausal women are often reluctant to exercise. Walking represents fewer barriers for women in midlife as it is inexpensive, easily accessible, and has low risk of injury. Sustained walking could serve as an alternative to hormone therapy or as a beneficial addition to hormone therapy or pharmaceutical drugs. The video hints to the findings of the scoping review designed to explore the current literature on the therapeutic effect of walking programs on menopause-related symptoms and risk factors. Limitations are discussed as well as suggestions for future research.
Creator: No sponsor
Created by Mayo Clinic
Duration: 4:22
The video reviews the findings from our paper entitled “Associations of Pituitary-Ovarian Hormones and White Matter Hyperintensities in Recently Menopausal Women using Hormone Therapy.” In recently menopausal women participating in the Kronos Early Estrogen Prevention Study (KEEPS), greater increases in estrone associated with smaller increases in WMH volume in both the transdermal estradiol and oral conjugated equine estrogen groups. In addition, greater decreases in FSH associated with smaller increases in WMH volume over time but only in women using the transdermal estrogen. Our results demonstrate that the type of hormone therapy used during menopause contributes to different levels of circulating hormones which then may have different impact on brain structure during treatment.
Creator: Purim Ruanphoo, MD.
Duration: 3:06
Introduction to the RCT of vaginal CO2 laser and sham procedure in treating vaginal atrophy.
Creator: CU-Anschutz Medical Campus, Office of Communications (contact Kristen O’Neill)
Duration: 1:51
C. Neill Epperson, MD, Chair and Robert Freedman Endowed Professor of Psychiatry at the University of Colorado-Anschutz Medical Campus highlights the significance of their study focusing on subjective and objective executive function difficulties after surgical menopause. While negative mood states (anxiety/depression) are common among individuals who endorse adverse childhood experiences (ACEs), these symptoms did not fully explain the relationship between ACEs and subjective executive function complaints or performance on working memory and sustained attention tasks. These data suggest that ACEs exert an enduring negative impact on cognition among women who experience new-onset executive function complaints after RRSO.
Creator: James Smith
Duration: 1:56
This video briefly raises the question of whether climate change will increase the incidence of menopausal hot flashes as raised in our related commentary. It challenges readers to consider what they can do to help us understand this more and prepare for these potential impacts.
Creator: Michael Shikany
Duration: 5:16
This video provides a brief overview of the Menopause manuscript, Associations of Social, Physical, and Financial Factors with Diet Quality Among Older, Community-dwelling Women
Creator: Alison Shea
Duration: 5:07
The menopause transition is a vulnerable time for mental health and it is important to better understand the risk factors for depression during this time. This study using baseline data from the Canadian Longitudinal Study on Aging shows that premature menopause and the use of hormone therapy, as well as low education, low household income, living alone, being nulliparous, and having low social support are associated with current depression measured using the Center for Epidemiologic studies Short Depression Scale.
Creator: Bence Kozma MD PhD / No Sponsor
Duration: 3:15
Many studies suggest that zinc levels may correlate with some vaginal conditions, but the role in the diagnosis of Genitourinary syndrome of Menopause or Vulvovaginal Atrophy is not known. Cervicovaginal lavage has been widely used to investigate changes in the vagina. In our prospective cohort study the multivariate regression model revealed a significant association between vaginal atrophy and cervicovaginal lavage zinc levels. Measuring the amount of zinc in cervicovaginal lavage could aid in the diagnosis of Genitourinary syndrome of Menopause. Zinc levels of cervicovaginal lavage could be used as a new marker of vaginal atrophy.
Creator: Hyun-Jin Kim
Duration: 3:19
Marriage is an important social factor that can provide protection against harmful health outcomes. There may be sex differences in the response to stress from a without spouse status. Clinicians should consider their marital status to predict subsequent cardiovascular disease.
Creator: Dr Nadav Michaan
Duration: 3:13
This video summarizes our work regarding the accuracy of ascites fluid in the diagnosis of ovarian cancer among post-menopausal patients (accuracy, sensitivity, specificity, negative and positive predictive values)
Creator: Dostogir Harun with the help of Dr. Mahfuj Alam
Duration: 2:52
This video is the summary of the article entitled ‘Knowledge and associated attitudes with menopause among women aged 45-60 years: A pilot study among rural and urban women in Bangladesh’. Happy to accept HTML if sponsor wants to place a logo or image file.
Creator: Creator: Rowan University Clinical Health And Social Experiences (CHASE) research team
Duration: 4:53
Detailed description of new research demonstrating that different quantification methods for measuring midlife women’s physical activity produce meaningfully different conclusions about activity engagement in this population.
Creator: Chulmin Lee
Duration: 3:18
Gabapentin is a plausible option for treating hot flush in menopause, especially when hormone therapy is contraindicated. This meta-analysis including 7 papers shows gabapentin reduces frequency, duration and intensity of vasomotor symptoms. Side effects such as dizziness and somnolence are tolerable.
Creator: Luiz Gustavo Oliveira Brito
Duration: 4:22
This video explains the reasons for performing this study and the main findings when we compared women with premature ovarian insufficiency versus a control group with regard to pelvic floor disorders.
Creator: Christy Costanian
Duration: 3:36
The purpose of this study was to investigate whether postmenopausal hormone therapy (HT) use interacts with diabetes, a risk factor for several age-related eye diseases. The study found that long-term HT use and type 2 diabetes interact in their relationship with cataract such that the odds of cataract is highest in that group.
Creator: Holly Thomas
Duration: 2:44
Dr. Holly Thomas, Associate Professor of Medicinefrom the University of Pittsburgh describes herresearch, in which she conducted interviews andfocus groups with women aged 60 and older toidentify causes of low libido. Postmenopausalvaginal symptoms, erectile dysfunction in malepartners, and life stressors were identified as majorcontributors. She ends with recommendations forhealthcare providers.
Creator: Carolyn J. Crandall, MD, MS
Duration: 4:34
In this video, Dr. Carolyn J. Crandall describes the key findings and clinical “take-home messages” of the systematic review regarding safety of vaginal estrogens that her team recently performed.
Creator: Sheida Zolfaghari
Duration: 1:36
Sleep disturbances are among the important problems that involve women after menopause. Despite of several studies about the relationship between menopause and sleep, there are still some controversies. In this study with a large sample size on the Canadian population, we studied different types of sleep disorders. Our findings revealed that menopause is associated with sleep onset insomnia disorder and obstructive sleep apnea. But we were not able to find an association between menopause and sleep maintenance insomnia disorder, daytime somnolence, rapid eye movement sleep behavior disorder and restless leg syndrome.
Creator: Pauline Maki
Duration: 3:31
This video describes results from a recent study examining the association between physiologic hot flashes and brain function as women learn and remember words.
Creator: Benjamin S. Harris, MD, MPH
Duration: 2:49
The risks and benefits of hormone therapy in perimenopausal women have been extensively studied. Less is known about hormone therapy in breast or gynecologic cancer survivors and risk of cancer recurrence. We reviewed the available data to determine whether hormone therapy is safe for breast, ovarian, endometrial, and cervical cancer survivors. We also present a mechanism of reducing breast cancer incidence through estrogen-driven apoptosis pathways, and discuss the role of progestins in the growth of breast cancer stem cells. These concepts are a foundation for future research into the role of hormone replacement in treatment and prevention of breast cancer.
Creator: Elizabeth J. Pekas
Duration: 4:28
Menopause is often accompanied by an age-associated hormonal decline, elevated blood pressure, and poor body composition, and these negative effects on health have been shown to improve following exercise training. The Vascular Research Lab at the University of Nebraska at Omaha revealed for the first time that 12 weeks of resistance band exercise training restores the aging-related hormonal decline while improving blood pressure and body composition in postmenopausal women with stage 1 hypertension.
Creator: Paige Wynne
Video Production Specialist
Creative and Digital Services
University of Illinois at Chicago
Duration: 3:34
In this video, we glimpse the significance of Uterine fibroid disease and highlights their unusual persistence in menopause women. Moreover, we discuss the possible available treatment options as well as the advantages and disadvantages of using hormonal therapy in this specific population.
Creator: Melanie Gibson-Helm
Duration: 4:01
In this video we describe a multiple-methods study to develop a Question Prompt List (QPL) for Early Menopause. The research resulted in a QPL for Early Menopause that is stakeholder informed, evidence-based, acceptable to women, and feasible to use in a clinic setting.
Creator: Martha Hickey
Duration: 6:46
What do healthcare professionals and high-risk women need to know about risk-reducing salpingo-oophorectomy?
Creator: David Rogant, Cleveland Clinic
Duration: 2:49
This video presents our impetus to embark on this randomized trial and the significance of our manuscript. We discuss the innovative use of CO2 fractional laser therapy for the treatment of genitourinary syndrome of menopause (GSM) and compare it to gold standard therapy. We summarize our thoughts regarding clinical applicability of the CO2 fractional laser for GSM and make our recommendations for future work in studying its long-term efficacy and safety.
Creator: Taryn Offenbacher
Duration: 3:11
The video provides an introduction to a review article in the journal regarding the evidence about effectiveness and safety of statin therapy in women.
Creator: Paulo Ricardo Prado Nunes
Duration: 03:26
- The exercise guidelines recommend 150 minutes/week of combined training (CT), aerobic and resistance exercises, for improvements in body composition (BC), muscle strength (MS) and physical function (PF). However, the lack of time and access to physical training facilities are commons barriers for people not to comply with the exercise guidelines.

- The high-intensity interval training (60 minutes/week - HIIT) is an exercise strategy to overcome the time commitment problem. However, there is no evidence regarding the HIIT effects on MS and PF.

- This study compared the effects of HIIT with CT on PF, BC and MS in obese postmenopausal women.
Creator: Sussex Health Outcomes Research & Education in Cancer; filmed and edited by Matt Bemment, Communication Assistant, Brighton and Sussex Medical School
Duration: 4:35
What do we really know about sex after menopause? This video summary reports on the results of a free-text analysis on sexual activity in over 4,400 postmenopausal women who took part in UKCTOCS, a large UK ovarian cancer screening trial. It shows that sexuality can change when we get older and that relationship status and health have a direct effect on sexuality and satisfaction. We believe it is important to raise awareness among women and healthcare professionals to increase the understanding of sexual issues women may face in later life.
Creator: Sharon J Parish
Duration: 3:22
This video is the author's summary of the Men's Perceptions and Attitudes Towards Menopause (MATE) survey, which is one of the first large studies surveying male partners of menopausal women. These men provided valuable insight into the impact of menopause on them and their partners, and revealed that most men discuss symptoms and are influential in helping their partners select treatments. Results support expanding patient education to include the male partners of menopausal women, who communicate with their partners about symptoms, may be influential in fostering lifestyle changes, and participate in decision-making regarding treatment.
Creator: Irwin Goldstein, MD
Duration: 3:48
This is a phase 3 pivotal trial of ospemifene versus placebo in women in menopause with moderate to severe vaginal dryness, a symptom of GSM. On physical examination, such women commonly have vulvar, vestibular and vaginal atrophy. This study, for the first time, utilized vulvar vestibular photography to objectively document changes in genital health. There were no changes noted in photography on placebo, however active therapy with a SERM resulted in regrowth of labia minora, normalization of the urethral gland prominence, resolution of the pallor and erythema of the vestibule and visualization of vestibular moisture. Visual assessment of genital health in such patients should be utilized in future trials.
Creator: Beate Sydora
Duration: 4:52
The video highlights the clinical significance of assessing quality of life in addition to menopause symptom severity in specialized menopause clinics. Considering both, QOL and symptom severity enables clinicians and health care workers to be able to consider each woman’s unique experience with menopause and propose treatment options to each woman’s specific needs. Furthermore, the video stresses the benefits of specialized menopause clinics offering multidisciplinary care and encourages the establishment of more clinics of this kind.