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February 2021 - Volume 28 - Issue 2

  • Isaac Schiff, MD
  • 1530-0374
  • 12 issues per year
  • Obstetrics & Gynecology 12/83
  • 2.942
In the study “Does age at the start of treatment for vaginal atrophy predict response to vaginal estrogen therapy? Post hoc analysis of data from a randomized clinical trial involving 205 women treated with 10μg estradiol vaginal tablets” by Derzko et al., it was shown that vaginal estrogen therapy improved the Vaginal Maturation Index (VMI), pH, and symptoms for women both less than 60 and over 60 years of age. However, the cellular responsiveness as measured by the VMI and vaginal pH was less effective in older women. Although both groups had a response, it was stronger in women under age 60 implying that if one is going to start treatment, the earlier the better.

Isaac Schiff, CM, MD
Editor-in-Chief

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