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November 2021 - Volume 28 - Issue 11

  • Isaac Schiff, MD
  • 1530-0374
  • 12 issues per year
  • Obstetrics & Gynecology 12/83
  • 2.953
In the paper “Menopausal hormone therapy and risk of incident hypertension: role of the route of estrogen administration and progestogens in the E3N cohort” by Madika et al, it was shown that menopausal hormone therapy may lead to an increased risk of hypertension, especially when the prescription includes oral estrogens and a progestin. Thus it is recommended to monitor the blood pressure of women on therapy and to modify the type of estrogen, route of administration, and progestin when indicated.

Also in this issue, the paper “Growth of surgically-confirmed leiomyomas in postmenopausal women: analysis of the influencing factors” by Shen et al demonstrated that fibroids continue to grow during the postmenopausal years even in the absence of estrogen therapy. Although one should consider leiomyosarcoma in the differential, we are reassured that this may be more frequent than once thought. It turns out that smaller fibroids compared with larger ones have relatively more growth, and the growth tends to be more associated with obesity.​

Isaac Schiff, CM, MD

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Current Issue Highlights

The effect of hormone therapy on breast density following risk-reducing salpingo-oophorectomy in women with an increased risk for breast and ovarian cancer

van Barele, Mark; Buis, Chistien C.M.; Brood-van Zanten, Monique M.A.; More

Menopause. 28(11):1307-1312, November 2021.

NAMS Practice Pearl

Vaginal CO2 laser therapy versus sham for genitourinary syndrome of menopause management: a systematic review and meta-analysis of randomized controlled trials

Khamis, Yasser; Abdelhakim, Ahmed Mohamed; Labib, Kareem; More

Menopause. 28(11):1316-1322, November 2021.

        -hosted by Dr Marla Shapiro 

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