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Clinical intervention to reduce central obesity and menopausal symptoms in women aged 35 to 55 years

Bitner, Diana L. MD, NCMP, FACOG1,2; Wild, Robert A. MD, PhD, MPH, NCMP3

doi: 10.1097/GME.0000000000000207
Original Articles

Objective Central obesity is a risk factor for cardiovascular disease and diabetes. Women commonly increase central fat deposition during the menopausal transition. The purpose of this demonstration project was to determine whether a personalized sex-specific intervention, WAIPointes (WAI stands for Who Am I), could reduce central obesity in women undergoing perimenopausal transition.

Methods Eighty-three of 103 women aged 35 to 55 years and experiencing symptoms of the menopausal transition completed a 6-month WAIPointes demonstration project; 75 consented to data review.

Sex-specific history was obtained on visit 1; directed physical examination for body mass index, body fat percentage, waist circumference, and blood pressure were performed at each of four or five subsequent monthly visits. Other tests were ordered as necessary to determine risk stratification.

Participants were assessed for menopause status, and they reported activity and menopausal symptoms at each visit. Personalized strategies for health improvement were developed in partnership. Women served as their own controls. Data from visit 2 were compared with data from visit 4.

Results The intervention reduced waist circumference and diastolic blood pressure and improved self-reported menopausal symptoms and physical activity levels.

Conclusions Although further study is needed, findings suggest that the WAIPointes program offers potential as an effective office-based clinical intervention to reduce cardiovascular risk factors and symptoms of menopause in women during the menopausal transition.

From the 1Department of Obstetrics, Gynecology, and Women’s Health, Spectrum Health Medical Group, Grand Rapids, MI; 2Department of Obstetrics, Gynecology, and Reproductive Biology, Michigan State University, Grand Rapids, MI; and 3Department of Obstetrics and Gynecology, University of Oklahoma College of Medicine, Oklahoma City, OK.

Received October 8, 2013; revised and accepted December 12, 2013.

Funding/support: This study was supported by Spectrum Health System. Kimberlee Roth of Outword Communications LLC provided editorial assistance in the preparation of this manuscript. Outword Communications LLC supplied paid editing services. (However, this does not indicate its endorsement of, agreement with, or responsibility for the content of this article.)

Financial disclosure/conflicts of interest: Copyright for WAIPointes is owned by Spectrum Health System.

Address correspondence to: Diana L. Bitner, MD, NCMP, FACOG, 3800 Lake Michigan Drive, Grand Rapids, MI 49524. E-mail:

© 2014 by The North American Menopause Society.