Objective:
To evaluate associations between
anxiety and severe impairment of
quality of life (QoL) in Latin American postmenopausal women.
Methods:
This was a secondary analysis of a multicenter cross-sectional study among postmenopausal women aged 40 to 59 from 11 Latin American countries. We evaluated
anxiety (The Goldberg Depression and
Anxiety Scale), and QoL (
Menopause Rating Scale [MRS]), and included sociodemographic, clinical, lifestyle, and anthropometric variables in the analysis. Poisson family generalized linear models with robust standard errors were used to estimate prevalence ratios (PRs) and 95% CIs. There were two adjusted models: a statistical model that included variables associated with the outcomes in bivariate analyses, and an epidemiologic model that included potentially confounding variables from literature review.
Results:
Data from 3,503 women were included; 61.9% had
anxiety (Goldberg). Severe QoL impairment (total MRS score ≥17) was present in 13.7% of women, as well as severe
symptoms (MRS subscales): urogenital (25.5%), psychological (18.5%), and somatic (4.5%).
Anxiety was independently associated with severe QoL impairment and severe
symptoms in the epidemiological (MRS total score: PR 3.6, 95% CI, 2.6-5.0; somatic: 5.1, 95% CI, 2.6-10.1; psychological: 2.8, 95% CI, 2.2-3.6; and urogenital: 1.4, 95% CI, 1.2-1.6) and the statistical model (MRS total score: PR 3.5, 95% CI, 2.6-4.9; somatic: 5.0, 95% CI, 2.5-9.9; psychological: 2.9, 95% CI, 2.2-3.7; and urogenital: 1.4; 95% CI, 1.2-1.6).
Conclusions:
In this postmenopausal Latin American sample,
anxiety was independently associated with severe QoL impairment. Hence, screening for
anxiety in this population is important.
