Clinical Corner: NAMS Practice PearlWhat are the concerns about custom-compounded “bioidentical” hormone therapy?Pinkerton, JoAnn V. MD, NCMP Author Information From the University of Virginia Midlife Health Center, Charlottesville, VA. Released August 6, 2014 Menopause 21(12):p 1298-1300, December 2014. | DOI: 10.1097/GME.0000000000000376 Buy Metrics Abstract Unsubstantiated claims, lack of scientific safety and efficacy data, and lack of quality control surround custom-compounded bioidentical hormone products. FDA-approved hormone therapy provides tested and regulated therapy without the risks of unregulated and untested custom preparations. © 2014 by The North American Menopause Society.