INVITED SPEAKERS ABSTRACTS
Unusual variants of cutaneous lymphomas
Primary cutaneous lymphomas (CLs) are the second most common group of extranodal non-Hodgkin's lymphomas. Cutaneous T-cell lymphomas (CTCLs) account for 60 to 65% of all primary CLs, whereas 20 to 25% of CLs are of B-cell origin. Besides the most common and well-known forms of CL, such as mycosis fungoides, Sezary Syndrome and follicular B-cell lymphomas, there are some rare and unusual variants of CL that represent about 10% of lymphoproliferative skin infiltrates and affect the skin primarily or secondarily. Discussed in detail apart from CD30+ lymphoproliferative disorders are variants of mycosis spongoides such as follicular mycosis fungoides, pagetoid reticulosis and granulomatous slack skin, and some rare, but distinct primary cutaneous T-cell lymphomas such as primary aggressive epidermotropic CD8+cytotoxic T cell lymphoma, subcutaneous panniculitis-like T cell lymphoma, primary cutaneousgamma/delta lymphoma, primary cutaneous CD4+ small or medium pleomorphic T cell lymphoma, primary cutaneous peripheral T cell lymphoma, unspecified (2005 WHO/EORTC classification). The final diagnosis in CL is based on a constellation of clinical, histopathologic, and molecular-biologic criteria.© 2010 Lippincott Williams & Wilkins, Inc.