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P92 Kaposi Sarcoma in renal transplant patients

Somlai, B.a; Vegso, G.b; Toth, A.b; Langer, R.b

doi: 10.1097/01.cmr.0000382926.47273.c7
Kaposi's sarcoma

Departments of aDermatology and Venerology

bTransplantation and Surgery, Semmelweis University, Budapest, Hungary

Kaposi Sarcoma is a relatively common malignancy after kidney transplantation. Aim of the study is to determine the clinical characteristics of Kaposi Sarcoma and the impact of immunsuppression in renal transplant population.

Methods Medical history and follow-up of graftedpatients with Kaposi Sarcoma have been selected. The clinical data includingthe date of transplantation, time period between grafting and tumordevelopment, the applied immunsuppressive therapy and disease outcome have been recorded.

Results Among 3200 kidney transplants performed at the Department of Transplantation and Surgery, Semmelweis University between 1973 and 2010, 12 patients (10 men and 2 women) were identified with Kaposi Sarcoma. The average time between transplantation and tumor development was 19.6 months. 53.8% of the Kaposi Sarcoma developed in the first year after transplantation. Patients with organ involvement succumbed rapidly.

Conclusion The impactof immunsuppression is dominant in the development of Kaposi Sarcoma in renaltranspant recipients.

© 2010 Lippincott Williams & Wilkins, Inc.