ORIGINAL ARTICLES: EpidemiologySuperficial spreading melanoma an analysis of 97 702 cases using the SEER databaseSingh, Parmvir; Kim, Hee Jin; Schwartz, Robert A.Author Information aDermatology and Pathology, Rutgers-New Jersey Medical School bRutgers University School of Public Affairs and Administration, Newark, New Jersey, USA Correspondence to Robert A. Schwartz, MD, MPH, Rutgers-New Jersey Medical School, Medical Science Building H-576, 185 South Orange Avenue, Newark, NJ 07103, USA Tel: +1 973 972 6255; fax: +1 973 972 5877; e-mail: email@example.com Received July 19, 2015 Accepted February 5, 2016 Melanoma Research: August 2016 - Volume 26 - Issue 4 - p 395-400 doi: 10.1097/CMR.0000000000000245 Buy Metrics Abstract Superficial spreading melanoma (SSM) is the most common type of melanoma. Large, population-based studies analyzing the incidence and survival of SSM are limited. This retrospective study was designed to evaluate demographic factors influencing the incidence and survival of SSM using a national population-based database. The United States National Cancer Institute’s Surveillance, Epidemiology, and End Results registry was used to calculate incidence and disease-specific survival trends for SSM between 1973 and 2012. Patient data were stratified according to age, sex, race, ulceration, thickness, and stage. Of 97 702 patients, 52.66% were men, 94.93% were white, and 38.92% had a primary lesion on the trunk. The overall incidence is 5.987/100 000 and is increasing with an annual percentage change (APC) of 1.42%. Incidence increases with age, peaking at 70–79 years. Men (6.68/100 00, APC: 1.78) had a significantly higher incidence than women (5.565/100 000, APC: 1.10). A total of 79.16% of SSM are less than or equal to 1 mm and 92.32% are nonulcerated. The overall 5-year survival is 95.30% and is increasing steadily. Women (hazard ratio: 0.54), ‘other’ races (hazard ratio: 0.30), those with local disease, those with thin tumors, and those without ulceration had higher survival than their counterparts (P<0.0001). The incidence of this predominantly thin melanoma subtype is on the rise, creating enhanced concern. Primary and secondary prevention techniques should consider the mortality associated with thin melanoma. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.