ORIGINAL ARTICLESS-classification of sentinel lymph node biopsy predicts the results of complete regional lymph node dissectionFink, Astrid M.a; Weihsengruber, Felixb; Spangl, Bernhardc; Feichtinger, Hansd; Lilgenau, Nikolausb; Rappersberger, Klemensb; Jurecka, Wolfganga; Steiner, AndreasaAuthor Information aDepartment of Dermatology, Wilhelminenspital, Montleartstrasse 37, 1160 Vienna, Austria bDepartment of Dermatology, Krankenhaus Rudolfstiftung, Juchgasse 25, 1030 Vienna, Austria cApplied Statistics and Computer Science, University of Agricultural Science, Vienna, Gregor-Mendel-Street 33, 1180 Vienna, Austria dDepartment of Pathology, Krankenhaus Rudolfstiftung, Juchgasse 25,1030 Vienna, Austria Correspondence and requests for reprints to Dr Astrid M. Fink, Department of Dermatology, Wilhelminenspital, Montleartstrasse 37, A-1160 Vienna, Austria Tel: +43-1/49150 2701; fax: +43-1/49150 2709; e-mail: [email protected] Received 9 November 2004 Accepted (after revision) 6 May 2005 Melanoma Research: August 2005 - Volume 15 - Issue 4 - p 267-271 Buy Abstract The purpose of this study was to identify melanoma patients with positive sentinel lymph nodes (SLNs) at increased risk for further metastases in this specific lymph node basin. A series of consecutive patients with primary malignant melanoma stage I and II were evaluated retrospectively. The results of SLN biopsy in 26 patients with positive SLNs were compared with those of complete regional lymph node dissection (RLND) using the recently published S-classification of SLNs. The results of S-classification of SLNs were correlated with the outcome of complete RLND. There was a significant correlation between the S stage of positive SLNs and the results of complete RLND (P=0.02). Only patients with SIII stage (n=4) SLNs were found to have further metastases in the residual lymph node basin. The present study indicates that patients with SI stage and SII stage SLNs rarely have further metastases in the specific lymph node basin. © 2005 Lippincott Williams & Wilkins, Inc.