A single atrium is a rare congenital heart disease (CHD) involving zero atrial septal traces and preserved intact ventricular septum and atrioventricular valves, requiring careful surgical intervention. However, developing to Eisenmenger syndrome (ES) makes the surgery complicated. Based on bidirectional cardiac shunting, vegetation easily develops in case of bacterial infection.
We reported a 35-year-old woman with a single atrium, patent ductus arteriosus, pulmonary hypertension, and ES who developed infective endocarditis on her left ventricular outflow tract and complicated cerebral abscess and who underwent challenged medical treatment.
Infection was successfully controlled after 4-time change in antibiotics over 4 months. However, surgery is complicated for her.
The patient presented a relatively good outcome during follow-up for >6 months.
This case report suggests that patients with complex CHD should accept surgery therapy earlier before developing ES. It is imperative to avoid invasive interventions to prevent infectious endocarditis.
Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Correspondence: Wei Huang, Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing, 400016, China (e-mail: firstname.lastname@example.org).
Abbreviations: CHD = congenital heart disease, ECD = endocardial cushion defect, ES = Eisenmenger syndrome, PDA = patent ductus arteriosus.
How to cite this article: Wang W, Feng P, Wang L, Dong Q, Huang W. Endocarditis and bacterial brain abscess in a young woman with a single atrium, patent ductus arteriosus, and Eisenmenger syndrome. Medicine 2019;98:36(e17044).
All authors contributed to the study design, data collection, data analysis, and preparation of the manuscript.
Informed written consent was obtained from the patient for publication of this case report and accompanying images.
The authors have no conflicts of interest to disclose.
Received February 19, 2019
Received in revised form July 8, 2019
Accepted August 12, 2019
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