Another serious problem of DDLPS is that disease-related mortality of it is very poor (28%). In the present case, the patient has had no recurrence for 5 years. However, in the literature, other patients had recurrence after 5 and 14 postoperative years. Therefore, further careful observation is needed for our case. Complete surgical resection is the first choice of treatment for LPS. The effectiveness of adjuvant chemotherapy has remained unclear. In 2 cases of DDLPS, adjuvant chemotherapy (such as doxorubicin, dacarbazine, and ifosfamide) was performed, and no recurrence occurred. On the other hand, no-recurrence cases including ours were experienced without adjuvant chemotherapy.[12,16] Radiotherapy was associated with improved overall survival compared with surgery alone for a patient with retroperitoneal sarcoma. However, there is hesitation for performing radiotherapy for LPS originating from the bowel mesentery because of the possibility of ileitis. Indeed, there is only a single reference about radiotherapy as far as we investigated. These postoperative therapies should be considered depending on the patient's background such as performance status and age.
We are grateful for the cooperation of Ryuji Aoyama and Masayuki Fujioka for diagnosis of the patient.
Matsuo K, Kagota S, Shirai Y, and Inoue M performed the patient's care including the operation. Kataoka T performed pathological investigation. Matsuo K and Taniguchi K designed and drafted the manuscript. Lee SW and Uchiyama K reviewed and revised the manuscript.
Kentaro Matsuo: 0000-0002-3303-814X.
Kentaro Matsuo orcid: 0000-0002-3303-814X.
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