Original ArticlesReliability and Validity of the SF-12 Health Survey Among People With Severe Mental IllnessSalyers, Michelle P. PhD*; Bosworth, Hayden B. PhD†; Swanson, Jeffrey W. PhD‡; Lamb-Pagone, Jerilynn RN, MSN, CS§; Osher, Fred C. MD¶Author Information *From the Department of Psychology, Indiana University–Purdue University, Indianapolis, Indiana. †From the Departments of Medicine and of Psychiatry and Behavioral Sciences, Duke University Medical Center and Veterans Affairs Medical Center, Durham, North Carolina. ‡From the Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina. §From the School of Nursing, Yale University and Connecticut Valley Hospital, Middletown, Connecticut. ¶From the Center for Behavioral Health, Justice, and Public Policy, University of Maryland School of Medicine, Baltimore, Maryland. Received February 3, 2000; initial review completed April 5, 2000; accepted July 24, 2000. Address correspondence to: Michelle P. Salyers, PhD, Department of Psychology, LD 124, 402 N Blackford St, Indianapolis, IN 46202-3275. E-mail: [email protected] Medical Care: November 2000 - Volume 38 - Issue 11 - p 1141-1150 Buy Abstract Objective. The objective of this work was to assess the reliability and validity of the Medical Outcomes Study Short-Form 12-Item Health Survey (SF-12) in a large sample of people with severe mental illness (SMI). Methods. We examined the internal factor structure of the SF-12, compared component scores for this sample with normative levels, examined test-retest reliability, and examined convergent and divergent validity by comparing SF-12 scores to other indexes of physical and mental health. Results. The SF-12 distinguished this sample of people with SMI from the general population, was stable over a 1-week interval, consisted of 2 fairly distinct factors, and was related to physical and mental health indexes in expected ways. Conclusions. The SF-12 appears to be a psychometrically sound instrument for measuring health-related quality of life for people with SMI. © 2000 Lippincott Williams & Wilkins, Inc.