Article: PDF OnlyCorrelation of Cerebral Perfusion Pressure and Glasgow Coma Scale to OutcomeCHANGARIS, DAVID G. M.D.*; McGRAW, C. PATRICK Ph.D.*; RICHARDSON, J. DAVID M.D.‡; GARRETSON, HENRY D. M.D., Ph.D.*; ARPIN, E. JOY M.D.*; SHIELDS, CHRISTOPHER B. M.D.* Author Information From the * Division of Neurological Surgery, the ‡Department of Surgery, University of Louisville School of Medicine, Louisville, Kentucky. The Journal of Trauma: Injury, Infection, and Critical Care: September 1987 - Volume 27 - Issue 9 - p 1007-1013 Buy Abstract Cerebral Perfusion Pressures (CPP) and Glasgow Coma Scale (GCS) scores were monitored to guide the management of severely head-injured patients. These measures were correlated to outcome (Glasgow Outcome Scale-GOS) in 136 consecutive patients at least 1 year after injury. The GOS showed highly significant positive correlations to either CPP or GCS assessments (p <0.001). Two parameters that are correlated with subsequent death in most patients include 1) highest (h) GCS = 3 or 4 (Day 1: 31 of 32 patients died, and Day 2: 19 of 19 patients died), and 2) CPP ≤60 mm Hg more than 33% of the hourly measures during Day 2 (36% of all subsequent deaths; 11% overlap with the highest Glasgow Coma Scale). The Day 2 measures identifying two groups that have a >75% incidence of “good outcome” or GOS = 4 or 5 include 1) hGCS ≤6 (N = 45) and 2) the average (a) CPP ≥90 mm Hg (N = 26). Of the 45 patients with a GOS = 4 or 5 who had both CPP and GCS recorded on the third day, 44 were identified by these “good outcome” parameters. © Williams & Wilkins 1987. All Rights Reserved.