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​TXA: Bedside to Battlefield (And Back Again)

 

 

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TXA: Bedside to Battlefield (And Back Again)
AAST Grand Round, March 2014

 

Presented by:
Dr. Joseph Rappold

Dr. Joseph Galante

 

Further reading:

Do all trauma patients benefit from tranexamic acid?
Valle EJ, Allen CJ, Van Haren RM, Jouria JM, Li H, Livingstone AS, Namias N, Schulman CI, Proctor KG.
J Trauma Acute Care Surg. 2014 Jun;76(6):1373-8.

 

Tranexamic acid corrects fibrinolysis in the presence of acidemia in a swine model of severe ischemic reperfusion.
DeBarros M, Hatch Q, Porta CR, Salgar S, Izenberg S, DuBose J, Eckert M, Martin M.
J Trauma Acute Care Surg. 2014 Mar;76(3):625-32; discussion 632-3.

 

The effects of tranexamic acid and prothrombin complex concentrate on the coagulopathy of trauma: an in vitro analysis of the impact of severe acidosis.
Porta CR, Nelson D, McVay D, Salgar S, Eckert M, Izenberg S, Martin MJ.
J Trauma Acute Care Surg. 2013 Dec;75(6):954-60.

 

Tranexamic acid in trauma: how should we use it?
Napolitano LM, Cohen MJ, Cotton BA, Schreiber MA, Moore EE.
J Trauma Acute Care Surg. 2013 Jun;74(6):1575-86.

 

Tranexamic acid autoinjector for prehospital care of noncompressible hemorrhage.
Culligan WB, Tien HC.
J Trauma. 2011 Nov;71(5 Suppl 1):S501-2.

 

Tranexamic acid for trauma patients: a critical review of the literature.
Cap AP, Baer DG, Orman JA, Aden J, Ryan K, Blackbourne LH.
J Trauma. 2011 Jul;71(1 Suppl):S9-14.