Secondary Logo

Journal Logo

Institutional members access full text with Ovid®

A different form of injury prevention

Successful screening and referral for human immunodeficiency virus and hepatitis C virus in a trauma population

Privette, Alicia R., MD; White, Benjamin, MD; Ferguson, Pamela L., PhD; Norcross, E. Douglas, MD; Richey, Lauren E., MD

Journal of Trauma and Acute Care Surgery: November 2018 - Volume 85 - Issue 5 - p 977–983
doi: 10.1097/TA.0000000000001991

BACKGROUND In the United States, millions of patients are living with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) (0.44% and 1.5%) and many are currently undiagnosed. Because highly effective treatments are now available, early identification of these patients is extremely important to achieve improved clinical outcomes. Prior data and trauma-associated risk factors suggest a higher prevalence of both diseases in the trauma population. We hypothesized that a screening program could be successfully initiated among trauma activation patients and that a referral and linkage-to-care program could be developed.

METHODS Hepatitis C virus and HIV screening tests were added to standard trauma activation laboratory orders at an academic Level I Trauma Center. Confirmatory viral load was sent when indicated. Patients with positive results were educated about their disease and referred to disease-specific follow-up. Data were collected prospectively from January 1, 2016, until June 30, 2017. Total and new diagnosis, referral rates, and linkage-to-care rates were analyzed.

RESULTS One thousand eight hundred ninety-eight patients arrived as trauma activations. One thousand two hundred seventeen (64.1%) patients were screened (Level A, 75.6%; Level B, 60.2%). Seven percent of the screened patients were initially positive, and 5.5% were confirmed positive. Rates of both HIV (1.1%) and HCV (4.4%) were almost triple the national average. Overall, 3.3% screened positive for a new diagnosis. For HCV, the rate of new diagnosis was twice the national average (3%). Over 85% of all cases were referred for follow-up, and the combined linkage-to-care rate was 43.3%.

CONCLUSION The majority of patients were screened and referred for follow-up, indicating successful implementation of our trauma screening program. Routine screening of trauma patients should be considered to increase diagnosis rate, increase linkage-to-care rates, and decrease disease transmission. These screening efforts would help bridge the health care gap that exists in the trauma population due to lower insurance rates and limited access to primary care.

LEVEL OF EVIDENCE Therapeutic/Care management, level III.

From the Medical University of South Carolina, Department of Surgery, Division of General Surgery (B.W., A.P., P.L.F., E.D.N.); and Louisiana State University Health Sciences Center, Department of Internal Medicine, Section of Infectious Disease (L.E.R.), New Orleans, LA.

Submitted: February 15, 2018, Revised: May 4, 2018, Accepted: May 11, 2018, Published online: May 30, 2018.

Presented at the 48th Annual Meeting of the Western Trauma Association, February 25 to March 2, 2018 in Whistler, Canada.

Address for reprints: Alicia Privette, MD, Medical University of South Carolina, 96 Jonathan Lucas St, MSC 613/CSB 420, Charleston, SC 29425; email:

© 2018 Lippincott Williams & Wilkins, Inc.