From the Department of Surgery, New England Medical Center (S.D.S., M.W.C., R.J.C.), Boston, Massachusetts, Department of Surgery, Medical University of South Carolina (D.J.C.), Charleston, South Carolina, and Department of Pathology and Laboratory Medicine, the Center for Thrombosis and Hemostasis, the Division of Laboratory Medicine, and the Department of Medicine, University of North Carolina at Chapel Hill (M.R., D.B., T.N.), Chapel Hill, North Carolina.
Submitted for publication January 28, 2004.
Accepted for publication February 20, 2004.
Supported by grants and contracts from Marine Polymer Technologies, Inc., Danvers, Massachusetts.
Presented, in part, at the Harvard University Department of Surgery Symposium, Clinical Activity and Mode of Action of the Hemostatic Agent Poly-N-Acetyl Glucosamine, February 25, 2003, Boston, Massachusetts.
Address for reprints: Steven D. Schwaitzberg, MD, Department of Surgery, New England Medical Center, 25 Harvard Street, Boston, MA 02111; email: [email protected].