ORIGINAL ARTICLE: PDF OnlyEFFECT OF INHALATION INJURY, BURN SIZE, AND AGE ON MORTALITY A STUDY OF 1447 CONSECUTIVE BURN PATIENTSSmith, David L. MDa; Cairns, Bruce A. MDa; Ramadan, Fuad MDa; Dalston, J. Scott BSb1; Fakhry, Samir M. MDa; Rutledge, Robert MDa; Meyer, Anthony A. MD, PhDa, b; Peterson, H. D. DDS, MDa, b Author Information aFrom the Department of Surgery, Chapel Hill, North Carolina. bJaycee Burn Center, University of North Carolina, Chapel Hill, North Carolina. The Journal of Trauma: Injury, Infection, and Critical Care 37(4):p 655-659, October 1994. Buy Abstract The relative impact of inhalation injury, burn size, and age on overall outcome following burn injury was examined in 1447 consecutive burn patients over a five and a half year period. The overall mortality for all patients was 9.5% (138 of 1447). The presence of inhalation injury, increasing burn size, and advancing age were all associated with an increased mortality (p > 0.01). The incidence of inhalation injury was 19.6% (284 of 1447) and correlated with increasing percent total body surface area (%TBSA) burn (r = 0.41, p < 0.01) and advancing age (r = 0.15, p < 0.01). The overall mortality for patients with inhalation injury was 31% (88 of 284) compared with 4.3% (50 of 1163) for those without inhalation injury. Using multivariate analysis inhalation injury was found tobe an important variable in determining outcome, but the most important factor in predicting mortality was %TBSA burn (accuracy = 92.8%) or a combination of %TBSA burn and patient age (accuracy = 93.0%). Adding inhalation injury only slightly improved the ability to predict mortality (accuracy = 93.3%). The presence of inhalation injury is significantly associated with mortality after thermal injury but adds little to the prediction of mortality using %TBSA and age alone. © Williams & Wilkins 1994. All Rights Reserved.