ORIGINAL ARTICLE: PDF OnlyCIOFFI WILLIAM G. M.D.; DEMEULES, JAMES E. M.D.; GAMELLI, RICHARD L. M.D.The Journal of Trauma: Injury, Infection, and Critical Care: July 1986 - p 638-642 Buy Abstract The effects of a 30% full-thickness total body surface area scald burn on in vitro mechanical cardiac function was studied in Sprague-Dawley rats. The findings were a 50% decrease in tension development and velocities of contraction and relaxation, when papillary muscle functions from sham and unresuscitated burned animals were compared. Fluid resuscitation synchronous with burning completely reversed the defects in papillary muscle function. This defect in function was partially transferable to normal muscles incubated in serum from burned rats. © Williams & Wilkins 1986. All Rights Reserved.