NARRATIVE REVIEWUpdate on Spinal Cord Injury ManagementRusso, Glenn S. MD*; Mangan, John J. MD, MHA†; Galetta, Matthew S. BS†; Boody, Barrett MD†; Bronson, Wesley MD†; Segar, Anand MD†; Kepler, Christopher K. MD, MBA†; Kurd, Mark F. MD†; Hilibrand, Alan S. MD†; Vaccaro, Alexander R. MD, PhD, MBA†; Schroeder, Gregory D. MD†Author Information *Connecticut Orthopaedics, Clinical Assistant Professor, Frank H. Netter School of Medicine at Quinnipiac University, Hamden, CT †Rothman Institute at Thomas Jefferson University Hospital, Philadelphia, PA This study was approved by the Institutional Review Board at Thomas Jefferson University Hospital. Each author certifies that our institution approved the human protocol for this investigation and that all investigations were conducted in conformity with ethical principles of research. Dr Schroeder has received funds to travel from AO Spine and Medtronic. Dr Vaccaro has consulted or has done independent contracting for DePuy, Medtronic, Stryker Spine, Globus, Stout Medical, Gerson Lehrman Group, Guidepoint Global, Medacorp, Innovative Surgical Design, Orthobullets, Ellipse, and Vertex. He has also served on the scientific advisory board/board of directors/committees for Flagship Surgical, AO Spine, Innovative Surgical Design, and Association of Collaborative Spine Research. Dr Vaccaro has received royalty payments from Medtronic, Stryker Spine, Globus, Aesculap, Thieme, Jaypee, Elsevier, and Taylor Francis/Hodder and Stoughton. He has stock/stock option ownership interests in Replication Medica, Globus, Paradigm Spine, Stout Medical, Progressive Spinal Technologies, Advanced Spinal Intellectual Properties, Spine Medica, Computational Biodynamics, Spinology, In Vivo, Flagship Surgical, Cytonics, Bonovo Orthopaedics, Electrocore, Gamma Spine, Location Based Intelligence, FlowPharma, R.S.I., Rothman Institute and Related Properties, Innovative Surgical Design, and Avaz Surgical. He has also served as deputy editor/editor of Spine. In addition, Dr Vaccaro has also provided expert testimony. The remaining authors declare no conflict of interest. Reprints: John J. Mangan, MD, MHA, Rothman Institute, 925 Chestnut Street, 5th Floor, Philadelphia, PA 19107 (e-mail: firstname.lastname@example.org). Clinical Spine Surgery: August 2020 - Volume 33 - Issue 7 - p 258-264 doi: 10.1097/BSD.0000000000000956 Buy Metrics Abstract The management of acute spinal cord injury requires a multidisciplinary approach to maximize patient outcomes and potential. Treatment of this injury involves both surgical and medical intervention. Medical intervention in acute spinal cord injury is aimed at decreasing the neurotoxic environment that occurs as part of the secondary injury. New neuroregenerative therapies are being developed. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.