Original ArticlesComparison of Minimally Invasive and Conventional Open Posterolateral Lumbar Fusion Using Magnetic Resonance Imaging and Retraction Pressure StudiesStevens, Kathryn J. MD*; Spenciner, David B. MS†; Griffiths, Karen L. MB, BCh*; Kim, Kee D. MD‡; Zwienenberg-Lee, Marike MD‡; Alamin, Todd MD§; Bammer, Roland PhD*Author Information *Department of Radiology, Stanford University Medical Center, Stanford, CA †Department of Orthopaedics, Brown Medical School/Rhode Island Hospital, Providence, RI ‡Department of Neurological Surgery, University of California Davis, Davis, CA §Department of Orthopaedic Surgery, Stanford University Medical Center, Stanford, CA Reprints: Dr. K. Stevens, Department of Radiology, Stanford University Medical Center, 300 Pasteur Dr., Rm. S-062A, Stanford, CA 94305 (e-mail: [email protected]). Received for publication August 3, 2005; accepted October 18, 2005 Journal of Spinal Disorders & Techniques: April 2006 - Volume 19 - Issue 2 - p 77-86 doi: 10.1097/01.bsd.0000193820.42522.d9 Buy Metrics Abstract Objective To determine whether minimally invasive lumbar spinal fusion results in less paraspinal muscle damage than conventional open posterior fusion. Methods The maximum intramuscular pressure (IMP) generated by a minimally invasive and standard open retractor was compared in cadavers using an ultra-miniature pressure transducer. In a second clinical study, eight patients with either minimally invasive or open posterolateral lumbar spinal fusion underwent magnetic resonance imaging (MRI) scanning approximately 6 months post surgery. MRI was used to estimate edema and atrophy within multifidus, with T2 mapping and diffusion-weighted imaging allowing quantification of differences between the two surgical techniques. Results IMP measured with the minimally invasive retractor was 1.4 versus 4.7 kPa with the open retractor (P<0.001). The minimally invasive retractor produced a transient maximal IMP only on initial expansion. Maximum IMP was constant throughout open retractor deployment. Striking visual differences in muscle edema were seen between open and minimally invasive groups on MRI. The mean T2 relaxation time at the level of fusion was 47 milliseconds in the minimally invasive and 90 milliseconds in the open group (P=0.013). The mean apparent diffusion coefficient was 1357×10−6 mm2/s and 1626×10−6 mm2/s (P=0.0184), respectively. Conclusions The peak IMP generated by the minimally invasive retractor was significantly less than with the open retractor. Postoperatively, less muscle edema was demonstrated after the minimally invasive lumbar spinal fusion, with lower mean T2 and apparent diffusion coefficient measurements supporting the hypothesis that less damage occurs using a minimally invasive approach. © 2006 Lippincott Williams & Wilkins, Inc.