Review ArticleOsteoporotic Spinal Deformity A Biomechanical Rationale for the Clinical Consequences and Treatment of Vertebral Body Compression FracturesYuan, Hansen A. MD*; Brown, Courtney W. MD†; Phillips, Frank M. MD‡Author Information From the *Spine Center, Department of Orthopaedic and Neurologic Surgery, State University of New York–Syracuse Medical Center, Syracuse, NY; †Panorama Orthopaedics, Golden, CO; and ‡University of Chicago Spine Center, Chicago, IL. Received for publication February 14, 2002; accepted June 12, 2003. Reprints: Hansen A. Yuan, MD, Spine Center, Department of Orthopaedic and Neurologic Surgery, State University of New York–Syracuse Medical Center, 550 Harrison Center, 130 Syracuse, NY 13202 (e-mail: [email protected]). Journal of Spinal Disorders & Techniques: June 2004 - Volume 17 - Issue 3 - p 236-242 Buy Abstract This review article develops a biomechanical rationale for the clinical consequences and treatment of osteoporotic vertebral body compression fracture. In patients with osteoporotic vertebral fractures and spinal deformity, altered spinal biomechanics and global spinal imbalance are important factors in the increased morbidity and mortality reported in this population. Severe spinal deformity impairs physical functioning, health, and quality of life. The spinal deformity itself, independent of pain, is a significant cause of disability. Spinal deformity is also an independent risk factor for hip fracture. Treatments directed at osteoporotic vertebral compression fractures should ideally address spinal deformity as well as pain. Balloon kyphoplasty, the minimally invasive technique of reduction and internal fixation of osteopenic vertebral body compression fractures that addresses pain and spinal deformity, is discussed. © 2004 Lippincott Williams & Wilkins, Inc.