Friday, December 1, 2017
What is the vmPFC and why is it important?
The ventromedial prefrontal cortex (vmPFC) has been implicated in a variety of key cognitive processes, many with analogy among humans, primates, and rodents; social cognition, emotional regulation, and reward/value-based decision-making. In this brief review, the authors pull together representative pieces of research in each of these areas (running the gambit of data from animal behavioral studies, to human fMRI studies, to studies of psychopathology), to paint a picture of the many functions of the vmPFC and how it networks with other parts of the brain in these various roles. Biological Psychiatry