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Early Screening for Autism Spectrum Disorders: Update on the Modified Checklist for Autism in Toddlers and Other Measures


Journal of Developmental & Behavioral Pediatrics: April 2006 - Volume 27 - Issue 2 - p S111-S119

Early intervention for autism spectrum disorders necessitates early detection. This need has led to widespread agreement across disciplines that screening is critical in very young children. Two screening issues are highlighted in this review. Level of screening refers to the type of sample: Level I is defined as an unselected sample, and Level II consists of selected children already identified as being at risk for a developmental disorder. Breadth or scope of screening refers to the range of difficulties the screening tool attempts to identify: broad screening instruments identify multiple range of developmental difficulties, whereas disorder-specific tools focus on a single disorder or class of disorders. Broad developmental instruments reviewed include the Parents' Evaluation of Developmental Status and the Ages and Stages Questionnaires; autism-specific tools reviewed include the Checklist for Autism in Toddlers, the Modified Checklist for Autism in Toddlers (M-CHAT), the Pervasive Developmental Disorders Screening Test, Second Edition, and the Screening Tool for Autism in Two-year-olds. The development of the M-CHAT, a Level I and Level II screening instrument, is described, and current research and clinical use of the M-CHAT are reviewed, including description of the structured follow-up interview which reduces the false-positive rate of the parent-report M-CHAT.

1Department of Psychology, Georgia State University, Atlanta, GA

2Division of Developmental-Behavioral Pediatrics, Department of Pediatrics, University of Connecticut School of Medicine, Farmington, CT; and Department of Psychology, University of Connecticut, Storrs, CT

Address for reprints: Diana L. Robins, Ph.D., Department of Psychology, Georgia State University, PO Box 5010, Atlanta, GA 30302-5010; e-mail:

© 2006 Lippincott Williams & Wilkins, Inc.