The purpose of this review is to determine the effectiveness of knee orthoses in the treatment of pain in unilateral compartment osteoarthritis (OA). Only studies that dealt with medial unilateral compartment knee OA and the use of a knee orthosis were selected. Of these articles, only experimental trials were selected based on the American Academy of Orthotists and Prosthetists State-of-the-Science Evidence Report Guidelines. Statistically significant pain reduction was noted by 73% of the studies reviewed, although all showed that there was pain reduction in the patients.
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