Although ectopic bone formation has been previously categorized using bone scans and serum AP levels, no quantitative measurement method has existed for assessing heterotopic ossification (HO) volume. Data from this study indicated that serum AP levels and white blood cells (WBC) were significant predictors of HO volumes. However, patient pain scores were not a valid predictor. In the future, the magnitude of serum AP levels and WBC counts may better predict the expected volume of trauma-related HO, but require large-scale studies with adequate power in order to confirm the findings of this small patient series.
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