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Treatment of early-onset scoliosis with growing rods in patients with neurofibromatosis-1

Carbone, Marco; Vittoria, Francesca; Del Sal, Alice

Journal of Pediatric Orthopaedics B: May 2019 - Volume 28 - Issue 3 - p 278–287
doi: 10.1097/BPB.0000000000000627

This study aimed at verifying the efficacy of growing rod treatment in patients affected by neurofibromatosis with early-onset scoliosis. The authors present a retrospective case study of seven children treated between 2001 and 2017. Mean age at initial surgery was 7.2 years. Mean Cobb angle was 82.7°. Lengthening was performed once a year. Mean Cobb angle at last follow-up was 50.1°. Mean spinal growth was 13.6 mm/year, with regular gain during lengthening procedures. Mean follow-up period was 7 years after the first surgery. Three patients underwent final fusion. Complications were one proximal junctional kyphosis, nine rod breakages, and one hook dislocation.

Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy

Correspondence to Marco Carbone, MD, IRCCS Materno Infantile Burlo Garofolo, Trieste 34137, Italy Tel: +39 040 378 5254; e-mail:

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