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Clinical experiences of focal periphyseal edema zones in adolescent knees: case reports

Ueyama, Hidekia,b; Kitano, Toshiob; Nakagawa, Keisukeb; Aono, Masanaria

Journal of Pediatric Orthopaedics B: January 2018 - Volume 27 - Issue 1 - p 26–30
doi: 10.1097/BPB.0000000000000388

Focal periphyseal edema (FOPE) zones were first described in 2011. The aim of this report was to investigate the clinical course of patients with FOPE zones. Three adolescent patients with a FOPE zone in the knee were treated and observed for a maximum of 2 years. No symptoms or leg-length discrepancy developed at the final follow-up after conservative therapies. This is the first report on the follow-up of FOPE zones with a maximum of 2 years. The results suggest that observation of FOPE zones may be sufficient without invasive examinations and treatment.

aDepartment of Orthopedic Surgery

bDepartment of Pediatric Orthopedic Surgery, Osaka City General Hospital, Osaka, Japan

Correspondence to Hideki Ueyama, M.D, Department of Orthopedic Surgery, Osaka City General Hospital, Miyakojimahondori 2-13-22, Miyakojima Ward, Osaka City, Osaka 5340021, Japan Tel: +81 6 6929 1221; fax: +81 6 6929 2041; e-mail:

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