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Scoliosis secondary to ganglioneuroma: a case report and up to date literature review

D’Eufemia, Patriziaa; Properzi, Enricoa; Palombaro, Martaa; Lodato, Valentinaa; Mellino, Lorettaa; Tetti, Martinaa; Martini, Lorenab; Persiani, Pietrob

Journal of Pediatric Orthopaedics B: July 2014 - Volume 23 - Issue 4 - p 322–327
doi: 10.1097/BPB.0000000000000040

Idiopathic scoliosis is the most common form of spinal deformity in children. However, secondary causes of scoliosis, such as ganglioneuroma, should be always considered to avoid wrong diagnosis, and further investigations are required when there are atypical signs. We report a case of ganglioneuroma misdiagnosed as idiopathic scoliosis and review the literature to identify the red flags useful for physicians during the evaluation of a child with scoliosis. On the basis of both clinical and radiographic criteria that emerged from this study, we propose an algorithm that could help in the differential diagnosis, suggesting when to perform an MRI.

Departments of aPediatrics

bOrthopaedics and Traumatology, ‘Sapienza’, University of Rome

Correspondence to Patrizia D’Eufemia, MD, Department of Pediatrics, ‘Sapienza’, University of Rome, Viale Regina Elena 324, 00161 Rome, Italy Tel: +39 06 49979250; fax: +39 06 49979251; e-mail:

© 2014 by Lippincott Williams & Wilkins, Inc.