PELVIS AND HIPEosinophilic granuloma of the ischium in an infantDurakbasa, Mehmet Oguz; Okan, Nedret; Kose, Ozkan; Gorgec, MucahitAuthor Information Haydarpasa Numune Education and Research Hospital, Istanbul, Turkey Correspondence to Mehmet Oguz Durakbasa, MD, Soyak Gokyuzu Konutlari, C Blok, D:45, Barbaros Mahallesi, Karayollari Site Sokak, No. 5, 34662 Uskudar-Istanbul, Turkey Tel: +90 532 765 24 42; e-mail: [email protected] Journal of Pediatric Orthopaedics B: May 2008 - Volume 17 - Issue 3 - p 125-127 doi: 10.1097/BPB.0b013e3282fb028f Buy Metrics Abstract This report presents an infant with a solitary eosinophilic granuloma (EG) in an unusual localization at an unusual age treated solely by vinblastine. A solitary EG of the right ischium was detected in a 17-month-old infant as confirmed by a computerized tomography-guided biopsy. He was treated with vinblastine, which was given 6 mg/m2 per week for a total of six doses. A complete cure was obtained as confirmed by a disease-free follow-up period of 5 years. Chemotherapy is an effective treatment option for a solitary EG in young children considering the risk of dissemination. Moreover, if the disease involves an area where surgery is considered difficult and morbid, or if it involves soft tissues, single-drug chemotherapy can be considered for treatment. © 2008 Lippincott Williams & Wilkins, Inc.