OSTEOGENESIS IMPERFECTAGrowth and progression of adolescent idiopathic scoliosis in girlsYlikoski, Mauno Author Information ORTON Orthopaedic Hospital, Invalid Foundation, Helsinki, Finland Sponsorship: This study was supported by Fortum (Neste). Correspondence and requests for reprints to Mauno Ylikoski, ORTON Orthopaedic Hospital, Invalid Foundation, Tenholantie 10, FIN-00280 Helsinki, Finland Tel: +358 9 4748 6238; fax: +358 9 4748 2401; e-mail: [email protected] Journal of Pediatric Orthopaedics B 14(5):p 320-324, September 2005. Buy Abstract The progression velocity of scoliosis was studied for 535 consecutive girls with untreated adolescent idiopathic scoliosis. At the first visit the mean age of the patients was 13.9 years (range 9–19 years), the mean magnitude of the major curves was 23.4° (range 5–60°), and that of the minor curves 16.4° (range 0–49°). The median follow-up time was 1.1 years (mean 1.4, range 0.5–6.3 years). The right thoracic curves were most progressive. In the major left thoracic and left lumbar curve types, initial minor curves progressed faster than major curves. The scoliosis progressed faster in patients with minor thoracic kyphosis. In these patients major right thoracic curves were more common. The progression of scoliosis was clearly dependent on the growth velocity, also, the greater the curve at the first visit, the greater was the progression. The progression was most notable with a growth velocity of ≥2 cm/year, at ages between 9 and 13 years, bone ages between 9 and 14 years, Risser signs 0–1, and between 0.5–2 years before menarche. © 2005 Lippincott Williams & Wilkins, Inc.