Feature Articles: Nursing Continuing Professional DevelopmentExploring Perinatal Nursing Care for Opioid Use Disorder Knowledge, Stigma, and CompassionKantrowitz-Gordon, Ira PhD, CNM; Price, Cynthia PhD, MA; Rudolf, Vania MD, MPH; Downey, Georgia BSN, RN; Castagnola, Kelsey BSN, RN Author Information Child, Family, and Population Health Nursing (Dr Kantrowitz-Gordon and Mss Downey and Castagnola) and Biobehavioral Nursing and Health Informatics (Dr Price), University of Washington School of Nursing, Seattle; and Addiction Recovery Services, Swedish Medical Center, Seattle, Washington (Dr Rudolf). Corresponding Author: Ira Kantrowitz-Gordon, PhD, CNM, University of Washington School of Nursing, Box 357262, 1959 NE Pacific St, Seattle, WA 98195 ([email protected]). This work was supported by the University of Washington School of Nursing Intramural Research Program, Suzanne E. Van Hooser fund. The funding organization had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication. Disclosure: The authors have disclosed that they have no significant relationships with, or financial interest in, any commercial companies pertaining to this article. Each author has indicated that he or she has met the journal's requirements for Authorship. Submitted for publication: March 25, 2021; accepted for publication: May 1, 2021. The Journal of Perinatal & Neonatal Nursing 36(4):p 353-361, October/December 2022. | DOI: 10.1097/JPN.0000000000000587 Buy CE Test Metrics Abstract The opioid epidemic has greatly increased the number of pregnant women with opioid use and newborns exposed to opioids in utero. Mothers with opioid use disorder can face stigma by nurses in perinatal care settings, contributing to negative care experiences. A survey was distributed to nurses caring for mothers and newborns exposed to opioids in a large urban hospital in the Pacific Northwest United States (n = 89) from March to July 2019. Survey measures included participant characteristics, attitude toward substance use in pregnancy and postpartum (stigma, compassion satisfaction, comfort, and knowledge), and open-ended questions. Relationships among variables and questionnaire items were examined using Pearson's correlations, 2-sample t tests, and simultaneous multiple linear regression. Qualitative description was used to analyze open-ended questions. Nurses' stigma was negatively correlated with compassion satisfaction (r = −0.63), feeling knowledgeable (r = −0.36), and comfortable in providing care to this population (r = −0.44). Nurses identified defensiveness, lack of trust, and inadequate social support as key challenges in this patient population. Nurses suggested more support for mothers and nurses, increased nursing education, and clinical guidelines to improve clinical practice and foster therapeutic relationships. Findings highlight potential strategies to improve nursing care for chemically dependent mothers and their infants. These strategies may offer practical approaches to reduce stigma, develop therapeutic relationships, and improve patient outcomes. © 2022 Wolters Kluwer Health, Inc. All rights reserved.