Feature ArticlesEffectiveness of Delayed Cord Clamping in Reducing Postdelivery Complications in Preterm Infants A Systematic ReviewChapman, Jessica DNP, APRN-CNP, NNP-BC; Marfurt, Stephanie PhD, RNC, APRN, CNE; Reid, Julie MSN, APRN-CNP, NNP-BC Author Information University of Oklahoma College of Nursing, Oklahoma City (Drs Chapman and Marfurt); and Intregris Baptist Medical Center, Oklahoma City, Oklahoma (Ms Reid). Corresponding Author: Jessica Chapman, DNP, APRN-CNP, NNP-BC, Department of Pediatrics, University of Oklahoma, 1200 Everett, 7th Floor North Pavilion, Oklahoma City, OK 73104 ([email protected]). The authors acknowledge University of Oklahoma Health Sciences Professor Dr A. Renee Leasure for her guidance through the development of this project, and Shari Clifton, OUHSC librarian, for her assistance in the literature review.This manuscript was completed as partial fulfillment of the requirements of the Doctor of Nursing Practice Program at the University of Oklahoma Health Sciences Center, College of Nursing.Supplemental digital content is available for this article. Direct URL citation appears in the printed text and is provided in the HTML and PDF versions of this article on the journal's Web site (www.jpnnjournal.com).Disclosure: The authors have disclosed that they have no significant relationships with, or financial interest in, any commercial companies pertaining to this article.Submitted for publication: December 17, 2015; accepted for publication: August 20, 2016. The Journal of Perinatal & Neonatal Nursing: October/December 2016 - Volume 30 - Issue 4 - p 372-378 doi: 10.1097/JPN.0000000000000215 Buy SDC Metrics Abstract This systematic review evaluates the effectiveness of delayed cord clamping in preterm infants on reducing postdelivery complications of anemia, hemodynamic instability, and the development of intraventricular hemorrhages. Interventions included varying durations of delayed cord clamping with and without cord milking as compared with immediate cord clamping, shorter delays in cord clamping, and delayed cord clamping without cord milking. A comprehensive search of randomized controlled trials, observational, cohort, and before-after studies was conducted between 1946 and 2015 in the electronic databases of Ovid MEDLINE, Embase, and Google Scholar. Studies were critically appraised using the Critical Appraisal Skills Program guidelines. Twenty-seven studies were included in the review from 1997 to 2015 from varying countries. Outcome measures included hematocrit/hemoglobin levels, measured or calculated blood volumes levels, number and volume of blood transfusions, presence of hypotension and need for treatment, and development of intraventricular hemorrhage. Delayed cord clamping can lead to improved outcomes measures in preterm infants. This review supports the current recommendation to perform delayed cord clamping during preterm deliveries. © 2016 Wolters Kluwer Health, Inc. All rights reserved.