Feature ArticlesShedding Light on Inherited Thrombophilias The Impact on PregnancyDobbenga-Rhodes, Yvonne MS, RNC-OB, RNC-NIC, CNS, CNS-BC, CPNAuthor Information Birthing Center, Washington Hospital Healthcare System, Fremont, California. Corresponding Author: Yvonne Dobbenga-Rhodes, MS, RNC-OB, RNC-NIC, CNS, CNS-BC, CPN, Birthing Center, Washington Hospital Healthcare System, 2000 Mowry Ave, Fremont CA 94538 (firstname.lastname@example.org). Disclosure: The author has disclosed that she has no significant relationships with, or financial interest in, any commercial companies pertaining to this article. Submitted for publication: August 3, 2015; accepted for publication: November 1, 2015. The Journal of Perinatal & Neonatal Nursing: January/March 2016 - Volume 30 - Issue 1 - p 36-44 doi: 10.1097/JPN.0000000000000146 Buy Metrics Abstract Physiologic changes of pregnancy result in a hypercoagulable state, placing the risk for venous thromboembolic events at 1 in 1600 births. Venous thromboembolic events are one of the leading causes of maternal mortality. A correlation among venous thromboembolic events, pregnancy complications, and inherited thrombophilia continues to be investigated. This article primarily focuses on the impact of inherited thrombophilias on pregnancy, labor, and birth and yet also addresses acquired thrombophilia. Prophylactic and therapeutic perinatal anticoagulation are lifesaving and pregnancy-sparing interventions. Interprofessional management of these high-risk pregnancies allows for increased surveillance to reduce perinatal morbidity and mortality. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.