Original ArticlesPsychopharmacology in PregnancyGjere, Niki A. MA, MS, RN, CSAuthor Information Clinical Nurse Specialist, Psychiatric Mental Health Nursing, Fairview Psychiatry and Behavioral Services, Fairview-University Medical Center, Minneapolis, Minnesota Submitted for publication: July 10, 2000; Accepted for publication: October 10, 2000 Denise G. Palmer, MS, RN, Perinatal Clinical Nurse Specialist, Fairview-University Medical Center, Minneapolis, Minnesota, is acknowledged for her support, encouragement, and ongoing consultation. The Journal of Perinatal & Neonatal Nursing: March 2001 - Volume 14 - Issue 4 - p 12–25 Buy Abstract Clinicians are confronted with challenging situations when working with women who are pregnant and have a co-existing mental illness. A risk benefit assessment is helpful when identifying possible care interventions. Psychopharmaceutical intervention is a consideration when nonpharmacological interventions are ineffective or inappropriate. Informed consent based on known and unknown risks to the mother and fetus should be obtained. Literature and case reports are contradictory and not conclusive about the risks of medications used for psychiatric illnesses. This article reviews the literature and provides clinical guidelines for antipsychotic medications, antidepressant medications, mood stabilizing medications, and antianxiety medications. Copyright © 2001 by Aspen Publishers, Inc.