Secondary Logo

Journal Logo

Institutional members access full text with Ovid®

Langerhans’ Cell Histiocytosis Masquerading as Caroli’s Disease

Narayanasamy Rajavelu, Thiagarajan MD*; Abimannane, Anitha MD*; Chinnaiah Govindhareddy, Delhi Kumar MD*; Kayal, Smita MD, DM; Kar, Rakhee MD, DM

Journal of Pediatric Hematology/Oncology: April 24, 2019 - Volume Publish Ahead of Print - Issue - p
doi: 10.1097/MPH.0000000000001495
Clinical and Laboratory Observations: PDF Only

Langerhans’ cell histiocytosis is an uncommon disease in children with varied clinical presentation. Multisystem form of this disorder usually affects organs like the bones, skin, liver, spleen, lungs, and the central nervous system. We describe here the clinical details of a 2-year-old girl with involvement of unusual sites like the parotid glands and the nails. This child also had multiple cystic lesions in the liver leading to a misdiagnosis of Caroli’s disease. Knowledge about the uncommon manifestations of this rare disorder helps in early diagnosis and treatment.

Departments of *Pediatrics

Medical Oncology

Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India

The authors declare no conflict of interest.

Reprints: Delhi Kumar Chinnaiah Govindhareddy, MD, Department of Pediatrics, JIPMER, Puducherry 605006, India (e-mail:

Received January 12, 2019

Accepted March 19, 2019

Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.