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Hemophilic Pseudotumor: An Important Differential Diagnosis of an Intracranial Mass

Anderson, Claire L. MD*; Alvarez, Ofelia MD*; Saigal, Gaurav MD; Davis, Joanna A. MD*

Journal of Pediatric Hematology/Oncology: April 2015 - Volume 37 - Issue 3 - p 219–222
doi: 10.1097/MPH.0000000000000187
Clinical and Laboratory Observations

Hemophilic pseudotumor is a rare complication of hemophilia. We present the case of a male toddler with moderate hemophilia A and cranial hemophilic pseudotumor managed with factor VIII infusions. We also provide a review of the literature. Recognition of this rare manifestation of this complication of hemophilia is important to provide correct treatment and avoid unnecessary investigations, particularly biopsy, which is contraindicated in this condition.

*Division of Pediatric Hematology-Oncology

Department of Radiology, University of Miami, Miami, FL

The authors declare no conflict of interest.

Reprints: Joanna A. Davis, MD, Department of Pediatrics (D-820), University of Miami Miller School of Medicine, P.O. Box 016960, Miami, FL 33101 (e-mail:

Received October 1, 2013

Accepted April 30, 2014

Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.