Long-term Complications and Management of Gastrointestinal Bleeding in Multifocal LymphangioendotheliomatosisShakir, Asiya K. MD*; Yu, Zhongxin MD†; Altaf, Muhammad Adnan MD*Journal of Pediatric Hematology/Oncology: October 16, 2018 - Volume Publish Ahead of Print - Issue - p doi: 10.1097/MPH.0000000000001324 Clinical and Laboratory Observations: PDF Only Buy PAP Abstract Author InformationAuthors Article MetricsMetrics Multifocal lymphangioendotheliomatosis with thrombocytopenia is a rare disease characterized by multiple cutaneous and gastrointestinal (GI) vascular lesions and thrombocytopenia refractory to platelet and blood cell transfusions. GI bleeding can become life-threatening in this condition. We report a case of multifocal lymphangioendotheliomatosis with thrombocytopenia in a male infant with isolated GI involvement, diagnosed when he was 3 months old. The patient was managed with daily aminocaproic acid, octreotide drip, and corticosteroids for 13 months after diagnosis; he had complete resolution of symptoms by 2 years of age and showed adequate height and gain by 5 years of age. This case adds to the paucity of data in the literature pertaining to the disease’s phenotypic variability, long-term clinical course, and management of GI bleeding. Departments of *Pediatrics, Division of Pediatric, Gastroenterology, Hepatology, and Nutrition †Pathology, Section of Pediatric Pathology, University of Oklahoma, Oklahoma City, OK The authors declare no conflict of interest. Reprints: Asiya K. Shakir, MD, 1200 Children’s Avenue, Suite 9E, Oklahoma City, OK 73104 (e-mail: email@example.com). Received March 20, 2018 Accepted August 26, 2018 Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.