Idiopathic pulmonary hemosiderosis is characterized by a triad of iron-deficiency anemia, hemoptysis, and radiographic diffuse lung infiltrates. However, the inconsistent initial presentation in children may cause a significant delay in diagnosis. Autoimmune reactivity seems to be the most acceptable theory of pathogenesis. We reported an 8-year-old boy presenting with a cough, fever, and difficulty breathing with a history of iron-deficiency anemia and an abnormal autoimmune response in the last 3 years. Perinuclear antineutrophil cytoplasmic antibodies were positive and chest computed tomography revealed patchy ground glass haziness. Bronchoalveolar lavage fluid showed hemosiderin-laden macrophages. The respiratory symptoms improved with oral corticosteroids.
Pediatric Hematology/Oncology Department, Dubai Hospital, Dubai Health Authority, Dubai, United Arab Emirates
The author declares no conflict of interest.
Reprints: Abdulrahman M. Al Jassmi, MBBS, MD, FACHARZT, MBA, Pediatric Hematology/Oncology Department, Dubai Hospital, Dubai Health Authority, P.O. Box 92227 Dubai, United Arab Emirates (e-mail: email@example.com).
Received September 10, 2018
Accepted April 15, 2019