Clinical and Laboratory ObservationsSuccessful Treatment of Central Nervous System Involvement in Posttransplant EBV-Related Lymphoproliferative Disease With Intrathecal Rituximab TherapyAslan, Fatma MD*; Güler, Salih MD*; Sezgin Evim, Melike MD*; Aslier, Mustafa MD†; Yazici, Zeynep MD‡; Öztürk Nazlioğlu, Hülya MD§; Meral Güneş, Adalet MD* Author Information Departments of *Pediatric Hematology †Otolaryngology-Head and Neck Surgery ‡Pediatric Radiology §Pathology, Uludag University Medical Faculty, Bursa, Turkey The authors declare no conflict of interest. Reprints: Melike Sezgin Evim, MD, Department of Pediatric Hematology and Pediatric Bone Marrow Transplantation, Uludag University Medical Faculty, 16059, Nilüfer/Bursa/Turkey (e-mail: [email protected]). Journal of Pediatric Hematology/Oncology: November 15, 2022 - Volume - Issue - 10.1097/MPH.0000000000002592 doi: 10.1097/MPH.0000000000002592 Buy PAP Metrics Abstract The posttransplant lymphoproliferative disease is a severe cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation. Central Nervous System involvement in EBV-related PTLD is rare, and there is no standard treatment recommendation. We present our patient and discuss other previously reported cases of EBV-associated PTLD with CNS involvement. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.