Online Articles: Original ArticleTaste Alteration in Children With Acute Lymphoblastic Leukemia Undergoing Maintenance TreatmentBilsin Kocamaz, Elif RN, BSN, PhD*; Çiçek Gümüş, Ecem RN, BSN, PhD†; Akbayram, Sinan MD‡; Yazici, Alper MD§ Author Information *Departments of Child Health and Diseases Nursing †Public Health Nursing, Gaziantep University Health Science Faculty, Şahinbey ‡Departments of Pediatric Hematology and Oncology §Otorhinolaryngology (Ear-Nose-Throat), Gaziantep University Faculty of Medical, Şehitkamil, Gaziantep, Turkey E.B.K., S.A., and A.Y. contributed to the planning and design of the study. E.Ç.G. assembled the data. E.B.K. performed the statistical analysis, interpreted the data and assisted with the revisions of the article. E.B.K., S.A., and E.Ç.G. read and approved the final article. This work was supported by the Gaziantep University Scientific Studies Projects (RM.16.01). The cost of the refill taste strips was met by the institution. The study budget was 206.88 Euros. The authors declare no conflict of interest. Reprints: Elif Bilsin Kocamaz, RN, BSN, PhD, Department of Child Health and Diseases Nursing, Gaziantep University Health Science Faculty, Şahinbey, Gaziantep 27000, Turkey (e-mail: [email protected]). Journal of Pediatric Hematology/Oncology: November 2022 - Volume 44 - Issue 8 - p e1053-e1056 doi: 10.1097/MPH.0000000000002458 Buy Metrics Abstract The purpose of the present study is to examine taste alteration in children with acute lymphoblastic leukemia (ALL) undergoing maintenance treatment. The population of the study was comprised of children with ALL between the ages of 7 and 18 who received maintenance treatment. The study sample was included 72 children (children with ALL:36 and healthy children: 36) determined by power analysis. This was a cross-sectional study. The children in both groups were applied to the taste test by the researcher. It was determined that there is a statistically significant difference (P<0.05) between sweet (sucrose), salty (sodium chloride), sour (citric acid), and bitter (quinine hydrochloride) taste test score averages of the children with ALL and healthy children and that the 4 taste test score averages are lower in the experiment group. The taste alterations were determined in the present study for children with ALL undergoing maintenance treatment. Problems of children with cancer such as loss of appetite, negative attitude toward food or weight loss can be reduced or prevented when taste alteration is determined in children with cancer thereby improving the feeding of the children thereby increasing their quality of life. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.