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Metabolic Changes in Children that Received Chemotherapy

Soto-Vega, Elena MD, PhD*; Carrillo-Vicente, Luis S. MD*,†; Vázquez, Juan C. MD; Pérez de Celis Herrero, María C. MD, PhD§; Muñoz-Pérez, María J. MD*,∥

Journal of Pediatric Hematology/Oncology: August 2019 - Volume 41 - Issue 6 - p 448–451
doi: 10.1097/MPH.0000000000001401
Original Articles

Cancer treatments are associated with short and long-effects. Epidemiological reports have revealed clinical features of metabolic syndrome (MS), obesity or overweight in young cancer survivors. The aim of the study was to examine the prevalence of unhealthy weight status and risk factors associated with MS related to chemotherapy. We study 52 pediatric cancer patients and analyze cholesterol, triglycerides, glycosylated hemoglobin, body mass index, waist circumference (WC), FINDRISC test. All the parameters were analyzed according to the percentile corresponding to sex and age of each child. The data show an important modification in weight, body mass index, and WC as in triglycerides, and cholesterol that could be associated with the development of MS. The variance analysis showed that the WC, triglycerides, and cholesterol are statistically correlated in our population. A follow-up for MS in children cancer survivor should be considered necessary.

*Faculty of Medicine, Universidad Anáhuac Puebla

Autonomuous Popular University of the State of Puebla

§Technologies for Health Laboratoy, FCC, Benemerita Universidad Autonoma de Puebla

Autonomous Benemerit University of Puebla, Puebla city

Chirstus Muguerza Hospital, North Campus, México city, México

The authors declare no conflict of interest.

Reprints: Elena Soto-Vega, MD, PhD, Faculty of Medicine, Universidad Anáhuac Puebla S.C., Calle Orión Norte S/N. La vista Country Club, San Andrés Cholula, Puebla C.P 72810, Mexico (e-mail:

Received October 13, 2018

Accepted December 3, 2018

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